Results 41 to 50 of about 133,997 (277)

Children with ASD show links between aberrant sound processing, social symptoms, and atypical auditory interhemispheric and thalamocortical functional connectivity

Developmental Cognitive Neuroscience, 2018
Autism spectrum disorder (ASD) is a complex and prevalent neurodevelopmental disorder characterized by social and communicative deficits, as well as repetitive behaviors and atypical sensitivity to sensory stimulation. Alterations in network connectivity
Annika C. Linke, R. Joanne Jao Keehn, Ellyn B. Pueschel, Inna Fishman, Ralph-Axel Müller   +4 more
doaj   +1 more source

Sensory sensitivity as a link between concussive traumatic brain injury and PTSD. [PDF]

, 2019
Traumatic brain injury (TBI) is one of the most common injuries to military personnel, a population often exposed to stressful stimuli and emotional trauma.
Fanselow, Michael S, Giza, Christopher C, Hoffman, Ann N, Hovda, David A, Lam, Jamie   +4 more
core   +1 more source

Psychopathology in Williams syndrome: the effect of individual differences across the lifespan [PDF]

, 2009
The present research aimed to comprehensively explore psychopathology in Williams syndrome (WS) across the lifespan and evaluate the relationship between psychopathology and age category (child or adult), gender and cognitive ability.
American Psychiatric Association, American Psychiatric Association, Helen F. Dodd, Jefferys D., Karmiloff-Smith A., Kaufman J., Melanie A. Porter, Mervis C. B., Pober B. R., Silverman W. K., Soni S., Switaj D. M., Woodcock R. W.   +12 more
core   +1 more source

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

Advanced Science, EarlyView.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon, Kyungchul Noh, Minkyu Hwang, Yoon‐Jung Kim, Unjin Lee, Yeon Joo Ryu, Je‐Kyung Ryu, Sang Beom Jun, Se‐Young Choi, Woo‐Hyun Cho, Sung Joong Lee   +10 more
wiley   +1 more source

Impact of Prematurity on Auditory Processing in Children

Pathophysiology, 2023
Prematurity is one of the most crucial risk factors negatively affecting the maturation of the auditory system. Children born preterm demonstrate high rates of hearing impairments. Auditory processing difficulties in preterm children might be a result of
Maria Y. Boboshko, Irina V. Savenko, Ekaterina S. Garbaruk, Veronika M. Knyazeva, Marina J. Vasilyeva   +4 more
doaj   +1 more source

Cross-modal extinction in a boy with severely autistic behaviour and high verbal intelligence [PDF]

, 2008
Anecdotal reports from individuals with autism suggest a loss of awareness to stimuli from one modality in the presence of stimuli from another. Here we document such a case in a detailed study of T.M., a 13-year-old boy with autism in whom significant ...
Adini, Y, Akshoomoff, N, Belmonte, MK, Bonneh, YS, Houde, JF, Iversen, PE, Kenet, T, Merzenich, MM, Moore, CI, Pei, F, Simon, HJ   +10 more
core   +1 more source

Electrical Control of the Transduction Channels’ Gating Force in Mechanosensory Hair Cells

Advanced Science, EarlyView.
The inner ear's hair cells rely on mechanosensitive ion channels to convert vibrations of their hair‐bundle into electrical signals. We show that varying the electrical potential (U) across the sensory epithelium modulates a key determinant of mechanosensitivity—the gating force (FG)—by modulating the gating swing (d), ranging from the size of the ...
Achille Joliot, Laure Stickel, Pascal Martin   +2 more
wiley   +1 more source

A comparison of the development of audiovisual integration in children with autism spectrum disorders and typically developing children [PDF]

, 2010
This study aimed to investigate the development of audiovisual integration in children with Autism Spectrum Disorder (ASD). Audiovisual integration was measured using the McGurk effect in children with ASD aged 7–16 years and typically developing ...
A Karmiloff-Smith, A Karmiloff-Smith, APA, B Gelder de, BG Tabachnick, C Tremblay, Claire Isaac, D Massaro, E Schopler, E Smith, EA Mongillo, Elizabeth Milne, G Iarocci, G Rippon, GA Calvert, GA Calvert, H McGurk, J Bebko, J Raven, J Williams, J Williams, JA Burack, JM Kilner, K Sekiyama, L Mottron, LM Dunn, M Bohning, M Rutter, M Smagt van der, MSC Thomas, Natalie Taylor, NS Hockley, S Dupont   +32 more
core   +1 more source

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan, Yuhua Zhang, Jiawei Du, Yongjun Zhu, Wei Cao, Yongjie Wei, Han Wu, Shiyu Qiu, Shiyi Pan, Lian Chen, Pingping Liang, Renjie Chai, Jianming Yang, Qiaojun Fang   +13 more
wiley   +1 more source

The gray matter volume of the amygdala is correlated with the perception of melodic intervals: a voxel-based morphometry study [PDF]

, 2014
Music is not simply a series of organized pitches, rhythms, and timbres, it is capable of evoking emotions. In the present study, voxel-based morphometry (VBM) was employed to explore the neural basis that may link music to emotion.
A Lamont, AJ Blood, AJ Calder, Alain De Beuckelaer, BK Hölzel, BM Nacewicz, C Gaser, CD Good, CF Doeller, CG Schmahl, E Bora, EA Phelps, F Faul, Feilong Ma, H Ising, I Peretz, J Ashburner, J Ashburner, J Ashburner, J LeDoux, J Savitz, Jia Liu, Jiahui Guo, JK White, Joel Snyder, JP Hamilton, KL Hyde, KS Button, L Cahill, LL Altshuler, M Davis, M Driessen, M Schwenzer, MA Rogers, ME Klein, Miao Xu, MT Mitterschiffthaler, N Gosselin, N Gosselin, N Tottenham, NE Foster, NE Foster, P Albouy, P Bermudez, P Broks, P Sah, P Schneider, PJ Gianaros, R Adolphs, R Adolphs, R Adolphs, S Brown, S Koelsch, S Koelsch, S Koelsch, S Koelsch, S Wehrum, SC Caetano, SE Sendelbach, SM Smith, SM Strakowski, SM Wang, T Ball, T Griffiths, U Nilsson, Xueting Li, Y Lerner, YI Sheline, YL Ferguson   +68 more
core   +7 more sources