Results 111 to 120 of about 927,003 (302)

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source

Abstract Representation of Movement Parameters in Basal Ganglia Output

Advanced Science, EarlyView.
The basal ganglia output provides a scalable velocity/position signal across behavioral contexts, supporting the idea that these variables are represented in the brain as abstract entities rather than as fixed changes in joint angles or specific sets of body effectors.
Ana Silvia Báez‐Cordero, Diana I. Ortega‐Romero, Claudia I. Pérez‐Díaz, Pavel E. Rueda‐Orozco   +3 more
wiley   +1 more source

Development of a non-human primate model for preclinical research of a novel auditory nerve implant

Frontiers in Neuroscience
The cochlear implant is a widely available hearing restoration technology that can provide speech understanding in quiet environments. This technology struggles however, in noisy settings or situations involving multiple speakers.
Inderbir Sondh, Luke A. Johnson, Geoffrey M. Ghose, Aaron Loveland, Lisa Larson, Hubert H. Lim, Hubert H. Lim, Hubert H. Lim, Meredith E. Adams   +8 more
doaj   +1 more source

Brain Network Dynamics of Local and Global Predictive Processing in Aging

Advanced Science, EarlyView.
Separation of concurrent whole‐brain networks in source‐reconstructed magnetoencephalography (MEG) data suggests that healthy aging reorganizes, rather than uniformly attenuates, neural responses elicited from hierarchical auditory violations. Enhanced early sensory deviance processing alongside reduced higher‐order cognitive responses suggests a large‐
Mathias Houe Andersen, Gemma Fernández‐Rubio, David R. Quiroga‐Martinez, Mattia Rosso, Mathias Klarlund, Kit Melissa Larsen, Hartwig Roman Siebner, Morten L. Kringelbach, Peter Vuust, Leonardo Bonetti   +9 more
wiley   +1 more source

Auditory Stimulation In Auditory Maturation Delay- A Case Study

Indian Journal of Public Health Research & Development
Introduction:  Auditory deficiencies have profound implications for the development of communication abilities, social exchange, and cognitive skills. Although advances in technological instrumentation have decreased the age at which it is possible to detect auditory deficits, an absence of electrophysiological or behavioural reaction to sound does not ...
null Mathew Nishanth A, null Steven Michael J, null Anusha Rao S, null Jaya Lakshmi P B   +3 more
openaire   +1 more source

Auditory stimulation and levels of anaesthesia [PDF]

Anaesthesia, 2017
openaire   +2 more sources

A Molecularly Defined Midbrain Circuit Mechanism for Sound‐Driven Defensive Behavior and Anxiety

Advanced Science, EarlyView.
Schematic diagram showing the Cbln2+ ICx–dPAG circuit for sound‐driven defensive and anxiety‐like behaviors. ABSTRACT The innate defense behaviors in response to threatening sounds play a fundamental role in survival. However, the neural circuits that detect threat‐relevant auditory cues and transform them into defensive behaviors remain poorly defined.
Jie Cao, Xingxing Lai, Lifang Huo, Zhouyuan Zheng, Qian Zhang, Zhimin Ye, Panpan Wan, Chao Ma, Congping Shang   +8 more
wiley   +1 more source

A perceptual framework for the auditory display of scientific data

, 1994
Presented at 2nd International Conference on Auditory Display (ICAD), Santa Fe, New Mexico, November 7-9, 1994.Presented at 2nd International Conference on Auditory Display (ICAD), Santa Fe, New Mexico, November 7-9, 1994.A principal requirement of the ...
Barrass, Stephen
core   +1 more source

Toward HRTF personalization: an auditory-perceptual evaluation of simulated and measured HRTFs

, 2008
Presented at the 14th International Conference on Auditory Display (ICAD2008) on June 24-27, 2008 in Paris, France.Presented at the 14th International Conference on Auditory Display (ICAD2008) on June 24-27, 2008 in Paris, France.Sound localization tests
Mokhtari, Parham, Nishimura, Ryouichi, Takemoto, Hironori   +2 more
core  

Computational and Data‐Driven Strategies for Lignocellulosic Biomass Valorization: From Multiscale Modeling to Digitalized Biorefinery Design

Advanced Science, EarlyView.
This Review critically connects structural recalcitrance, molecular modeling, solvent and catalyst design, pyrolysis, machine learning, reactor simulation, and FAIR digital infrastructure. Emphasis is placed on experimentally validated information transfer across scales, uncertainty and applicability domains, and the recycle, durability, techno ...
Abdullahi Bello Umar, Jiaxian Zheng, Xiangfeng Lin, Hongwu Liao, Haoqian Xu, Yufei Huang, Zaharaddeen Nasiru Garba, Adamu Uzairu, Weiwei Zhao, Zhanhui Yuan   +9 more
wiley   +1 more source