Phasic firing and coincidence detection by subthreshold negative feedback: divisive or subtractive or, better, both [PDF]
, 2017 Phasic neurons typically fire only for a fast-rising input, say at the onset of a step current, but not for steady or slow inputs, a property associated with type III excitability.
Huguet Casades, Gemma +2 more
core +2 more sources
The Geometry of Layer 2/3 Cortical Sound Processing in Slow Wave Sleep
Advanced Science, EarlyView.Sleep is associated with a sensory disconnection whose mechanisms remain elusive. Large neuronal population recordings in the auditory cortex revealed that, in NREM sleep, the neural code for sounds is highly similar to wakefulness, but coordinated modulations of neuron responsiveness intermittently disconnect the local cortical networks from sensory ...
Allan Muller +3 more
wiley +1 more source
Auditory Temporal Resolution in Individuals with Diabetes Mellitus Type 2
International Archives of Otorhinolaryngology, 2016 Introduction “Diabetes mellitus is a group of metabolic disorders characterized by elevated blood sugar and abnormalities in insulin secretion and action” (American Diabetes Association).
Rajkishor Mishra +2 more
doaj +1 more source
OPA1-related auditory neuropathy: site of lesion and outcome of cochlear implantation. [PDF]
, 2015 Hearing impairment is the second most prevalent clinical feature after optic atrophy in Dominant Optic Atrophy associated with mutations in the OPA1 gene.
Arslan, E +12 more
core +3 more sources
Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors
Advanced Science, EarlyView.Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen +8 more
wiley +1 more source
The role of auditory abilities in basic mechanisms of cognition in older adults
Frontiers in Aging Neuroscience, 2013 The aim of this study was to assess age-related differences between young and older adults in auditory abilities and to investigate the relationship between auditory abilities and basic mechanisms of cognition in older adults. Although there is a certain
Massimo eGrassi, Erika eBorella
doaj +1 more source
Long-Term Follow-Up of the Auditory Threshold After a Fully Implantable Middle Ear Implant. [PDF]
Front Neurol, 2022 Monini S +3 more
europepmc +1 more source
Complex networks in brain electrical activity
, 2005 We analyze the complex networks associated with brain electrical activity. Multichannel EEG measurements are first processed to obtain 3D voxel activations using the tomographic algorithm LORETA.
Fuentemilla, L. +4 more
core +1 more source
The psychophysics of absolute threshold and signal duration: A probabilistic approach [PDF]
, 2011 The absolute threshold for a tone depends on its duration; longer tones have lower thresholds. This effect has traditionally been explained in terms of ?temporal integration? involving the summation of energy or perceptual information over time.
Heil P. +5 more
core +1 more source
Subicular Astrocytes Govern Seizure‐Impaired Fear Memory
Advanced Science, EarlyView.Astrocytes in dorsal subiculum act as a critical modulator of seizure‐associated cognitive dysfunction, operating through a Ca2+‐dependent adenosine‐linked astrocyte‐neuron signaling pathway that disrupts neuronal circuit homeostasis. This research highlights the potential of astrocyte‐targeted interventions as a therapeutic strategy, moving beyond the
Yuying Shao +15 more
wiley +1 more source