Results 71 to 80 of about 213,745 (334)

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

Cocleostomia transcanal: resultados em longo prazo de um estudo de coorte Transcanal cochleostomy in cochlear implant surgery: long-term results of a cohort study

Brazilian Journal of Otorhinolaryngology, 2012
A técnica de acesso combinado (TAC) ao implante coclear (IC) é uma variação da técnica clássica de mastoidectomia e timpanotomia posterior (MPTA). A TAC combina um acesso transcanal à cocleostomia com uma timpanotomia posterior reduzida para a inserção ...
Michelle Lavinsky-Wolff, Luiz Lavinsky, Celso Dall'Igna, Joel Lavinsky, Ênio Setogutti, Manoela Chitolina Viletti   +5 more
doaj   +1 more source

Heschl's gyrus is more sensitive to tone level than non-primary auditory cortex [PDF]

, 2002
Previous neuroimaging studies generally demonstrate a growth in the cortical response with an increase in sound level. However, the details of the shape and topographic location of such growth remain largely unknown.
Alan R Palmer, Baumgart, Beagley, Belin, Binder, Bowtell, Bowtell, Brechmann, Burkhard, Dadson, Deborah A Hall, Evans, Friston, Friston, Friston, Galaburda, Giraud, Gutschalk, Hall, Hall, Hall, Heeger, Heil, Heil, Heledd C Hart, Hunton, Jancke, Kim, Lai, Lauter, Lockwood, Logothetis, Maes, Millen, Mohr, Mondt, Morosan, Ozdamar, Palmer, Pantev, Penhune, Pfingst, Phillips, Phillips, Phillips, Phillips, Rademacher, Rapin, Raushecker, Recanzone, Recanzone, Rees, Rivier, Rorden, Rutkowski, Shamma, Strainer, Suga, Talavage, Taniguchi, Viemeister, Waldvogel, Wallace, Weeks, Westbury, Yang, Zatorre   +66 more
core   +1 more source

Electrical Control of the Transduction Channels’ Gating Force in Mechanosensory Hair Cells

Advanced Science, EarlyView.
The inner ear's hair cells rely on mechanosensitive ion channels to convert vibrations of their hair‐bundle into electrical signals. We show that varying the electrical potential (U) across the sensory epithelium modulates a key determinant of mechanosensitivity—the gating force (FG)—by modulating the gating swing (d), ranging from the size of the ...
Achille Joliot, Laure Stickel, Pascal Martin   +2 more
wiley   +1 more source

Auditory Spectrum-Based Pitched Instrument Onset Detection [PDF]

, 2010
In this paper, a method for onset detection of music signals using auditory spectra is proposed. The auditory spectrogram provides a time-frequency representation that employs a sound processing model resembling the human auditory system.
Benetos, E., Stylianou, Y.
core   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Determination and evaluation of clinically efficient stopping criteria for the multiple auditory steady-state response technique [PDF]

, 2009
Background: Although the auditory steady-state response (ASSR) technique utilizes objective statistical detection algorithms to estimate behavioural hearing thresholds, the audiologist still has to decide when to terminate ASSR recordings introducing ...
D'Haenens, Wendy, Dhooge, Ingeborg, Vinck, Bart   +2 more
core   +1 more source

Non-parametric statistical thresholding for sparse magnetoencephalography source reconstructions. [PDF]

, 2012
Uncovering brain activity from magnetoencephalography (MEG) data requires solving an ill-posed inverse problem, greatly confounded by noise, interference, and correlated sources.
Nagarajan, Srikantan S, Owen, Julia P, Sekihara, Kensuke   +2 more
core   +1 more source

The Geometry of Layer 2/3 Cortical Sound Processing in Slow Wave Sleep

Advanced Science, EarlyView.
Sleep is associated with a sensory disconnection whose mechanisms remain elusive. Large neuronal population recordings in the auditory cortex revealed that, in NREM sleep, the neural code for sounds is highly similar to wakefulness, but coordinated modulations of neuron responsiveness intermittently disconnect the local cortical networks from sensory ...
Allan Muller, Anton Filipchuk, Sophie Bagur, Brice Bathellier   +3 more
wiley   +1 more source

Auditory frequency threshold comparisons of humans and pre-adolescent chimpanzees [PDF]

Auditory frequency threshold comparisons of humans and pre-adolescent ...
Farrer, D. N., Prim, M. M.
core   +1 more source