Results 111 to 120 of about 580,897 (336)

Efferocytosis‐Driven Polyamine Metabolism in Macrophages Enhances Cancer Stem Cell Enrichment after Chemotherapy in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
Chemotherapy‐induced efferocytosis drives ovarian cancer stem cell enrichment. By engulfing apoptotic cancer cells, macrophages upregulate ODC1 and produce putrescine, which elevates osteopontin (OPN) expression. Secreted OPN then activates the CD44 receptor on cancer cells, promoting stemness and chemoresistance.
Wenhan Li   +19 more
wiley   +1 more source

Stress‐Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.
Zhibo Shao   +18 more
wiley   +1 more source

Active Force Dynamics in Red Blood Cells Under Non‐Invasive Optical Tweezers

open access: yesAdvanced Science, EarlyView.
A non‐invasive method combines low‐power optical tweezers with high‐speed microscopy to simultaneously monitor local membrane forces and displacements in single human red blood cells. This dual‐channel approach reveals a mechano‐dynamic signature that correlates the cell's metabolic state with its mechanical activity. This energetic framework serves as
Arnau Dorn   +5 more
wiley   +1 more source

Dijital Çağda Sanat Eserinin Biricikliği Üzerine

open access: yesBodrum Journal of Art and Design, 2022
Walter Benjamin’in “Mekanik Yeniden Üretim Çağında Sanat Eseri” metninde tartışmaya açtığı sanat yapıtının biricikliği sorunsalı, yeniden üretim tekniklerinin gelişmesi ve çeşitlenmesi dolayısıyla günümüz dijital çağında da geçerliliğini korumaktadır ...
Batu Bozoğlu, Eda Çekil Konrat
doaj  

Supply Constraints and Housing Prices [PDF]

open access: yes
This paper analyzes the effects of land use constraints on housing prices. We provide a new framework for evaluating policy when mobility across regions is allowed but limited.
Saku Aura, Thomas Davidoff
core  

PRDM1+ Malignant Cells Mediate an Immunosuppressive Landscape and Resistance to Neoadjuvant Chemoradiotherapy and Immunotherapy in Esophageal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen   +12 more
wiley   +1 more source

“Chase Sound Boys Out of Earth”: The Aura of Dubplate Specials in Finnish Reggae Sound System Culture

open access: yesDancecult: Journal of Electronic Dance Music Culture, 2015
This study seeks to expand our understanding of how dubplate specials are produced, circulated, and culturally valued in the international reggae sound system culture of the dub diaspora by analysing the production and performance of “Chase the Devil ...
Kim Ramstedt
doaj  

Aura Ozone Monitoring Garden Lithograph [PDF]

open access: yes, 2006
This lithograph describes where ozone is found, how it is formed, and the effects of ozone on biological processes. How and why NASA studies ozone is covered along with how individuals can monitor ground level (tropospheric) ozone by starting their own ...

core  

Nasal pain as an aura: Amygdala origin? [PDF]

open access: bronze, 2020
Kyoung Heo   +4 more
openalex   +1 more source

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