Results 161 to 170 of about 536,441 (334)

Developing HaloTag and SNAP‐Tag Chemical Inducers of Dimerization to Probe Receptor Oligomerization and Downstream Signaling

open access: yesAngewandte Chemie International Edition, Accepted Article.
Controlling protein‐protein interactions is critical for dissecting signaling pathways, especially those initiated by ligand‐receptor interactions which alter receptor oligomerization and drive downstream signaling cascades. Traditional methods for driving protein‐protein complexes are using antibodies that face limitations in terms of stoichiometry ...
Johannes Broichhagen   +8 more
wiley   +1 more source

Redirecting the Peptide Cleavage Causes Protease Inactivation

open access: yesAngewandte Chemie International Edition, EarlyView.
Cysteine proteases catalyze substrate cleavage by a two‐step acyl transfer mechanism. Newly designed peptidic inhibitors of human cathepsin B with N‐terminal carbamate warheads undergo a redirected cleavage and generate non‐canonical covalent complexes.
Christian Breuer   +20 more
wiley   +1 more source

Axially symmetric stars in Einstein-Maxwell theory

open access: yes, 2018
In this work we show how to construct general relativistic star models with axial symmetry in the Einstein-Maxwell theory. Starting with a general axially symmetric interior fluid solution we show how to construct the corresponding electrically charged ...
Dariescu, Ciprian   +2 more
core  

GIXRD Study of PM6: Y12 Films for Stretchable OPV Applications

open access: yesJournal of Applied Polymer Science, EarlyView.
ABSTRACT Recent advancements in organic photovoltaics (OPVs) have focused on improving both efficiency and mechanical robustness, yet critical insights into the structural and mechanical properties of the materials remain underexplored, particularly in the context of intrinsically stretchable OPVs.
Lydia Abbassi   +8 more
wiley   +1 more source

Pensando el arte y la sociedad contemporáneos: la recepción del concepto benjaminiano de aura en Bourriaud y Michaud

open access: yesRevista Filosofía UIS, 2009
El artículo se propone pensar la cuestión del arte en la actualidad y su relación con lo político tomando como hilo conductor el concepto benjaminiano de aura y, en particular, sus reinterpretaciones contemporáneas en las obras de Nicolas Bourriaud e ...
Ana Inés Markman
doaj  

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