Results 41 to 50 of about 63,506 (310)

Coaxially Electrospun Myocardial dECM‐ Based Nanofibrous Scaffolds Demonstrate Enhanced Cardiomyocyte Biocompatibility

Advanced Healthcare Materials, EarlyView.
Our coaxial electrospinning system is capable of incorporating decellularized myocardial extracellular matrix in a core‐sheath configuration, creating nanofibrous scaffolds. These scaffolds, in turn, support the maintenance of functional cardiomyocytes adhered to the surface of these bioactive scaffolds.
Dhanusha N. Rajapakse, Mahtab Khodadadi, Kiran M. Ali, Suh Hee Cook, Bryson T. Proctor, Tanya Upadhyay, Daxian Zha, Fatema Tuj Jahura, Marziyeh Boosaliki, Jessica M. Gluck   +9 more
wiley   +1 more source

Microgel‐Based 3D Bioprinting: A Convergent Strategy Integrating Material Design, Jamming Dynamics, and Biological Function

Advanced Healthcare Materials, EarlyView.
Microgel‐based 3D printed constructs represent a compelling and versatile innovation for engineering architecturally complex, dynamically remodelable, and biocompatible structures with high structural fidelity and bioactivity. By integrating material design, biofabrication, and biological function, these systems enable the development of adaptive ...
Elena Ghighină, Andreea Ioana Dinu, Jana Ghițman   +2 more
wiley   +1 more source

An Imaging‐Guided, Patient‐Specific Guiding Aid (RWNGuide) for Safe and Reproducible Inner Ear Drug Delivery

Advanced Materials Technologies, EarlyView.
A patient‐specific, imaging‐guided aid enables precise and reproducible drug delivery to the inner ear. By guiding therapeutic agents directly to the round window niche, this approach reduces variability in drug localization, improves delivery safety, and addresses a critical bottleneck in inner ear therapy, offering a scalable strategy for precision ...
Yanjing Luo, Shanshan Jiang, Yimian Luo, Adele Moatti, Farnaz Matin‐Mann   +4 more
wiley   +1 more source

IL-6 signaling is required for the development and regeneration of ear cartilage in microtia

Frontiers in Cell and Developmental Biology
IntroductionCongenital microtia is a birth defect characterized by auricular underdevelopment, with unclear pathogenesis and unidentified pathogenic genes.MethodsDifferential expression analysis, weighted co-expression network analysis (WGCNA), protein ...
Wenkang Luan, Shujun Fan, Hanyi Jiang, Dongwen Jiang, Jinxiu Yang, Leren He   +5 more
doaj   +1 more source

Complex functional and epithetic rehabilitation after ablation of recurrent retroauricular basal cell carcinoma – a case study

GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW, 2017
The reconstruction of extended defects of the concha poses a complex challenge for plastic surgeons. In cases of subtotal ablation, an rn method designed especially for elderly oncological patients consists of epithetic rehabilitation. However, inserting
Reich, Waldemar, Exner, Anika, Winter, Eileen, Al-Nawas, Bilal, Eckert, Alexander Walter   +4 more
doaj   +1 more source

sleep and auricular acupressure

, 2023
88 midlife and elderly women who experienced poor sleep quality were grouped into auricular acupressure, auricular sham point pressure, and control group. Sleep quality and insomnia were measured using the PSQI and ISI.
Cheng, C (via Mendeley Data)
core   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Biofabrication of a shape-stable auricular structure for the reconstruction of ear deformities

Materials Today Bio, 2021
Bioengineering of the human auricle remains a significant challenge, where the complex and unique shape, the generation of high-quality neocartilage, and shape preservation are key factors.
I.A. Otto, P.E. Capendale, J.P. Garcia, M. de Ruijter, R.F.M. van Doremalen, M. Castilho, T. Lawson, M.W. Grinstaff, C.C. Breugem, M. Kon, R. Levato, J. Malda   +11 more
doaj   +1 more source

Fibrilação auricular: desafios e implicações na qualidade de vida e declínio cognitivo [PDF]

A fibrilação auricular é a arritmia cardíaca mais comum na prática clínica, afetando milhões de pessoas globalmente. Caracterizada pela desorganização da atividade elétrica nas aurículas, resulta em contrações auriculares ineficazes, muitas vezes rápidas,
Machado, Ana Mónica Macedo Mendonça, Pereira, M. Graça, Leite, Fernanda   +2 more
core   +1 more source

A Pathology‐Instructed Theranostic Platform with Mechanoadaptive and ROS‐Powered Nanobreathing Functions for Precision Myocardial Repair

Advanced Science, EarlyView.
We developed a pH responsive theranostic serum albumin hydrogel named BST, functionalized with MRI and CT probes and loaded with mitochondria targeted CAT‐SOD nanogels, that rapidly self repairs and mechanically stabilizes the infarcted myocardium, releases therapeutic nanogels and albumin under hypoxia induced acidosis to clear mitochondrial ROS ...
Zheng Luo, Cui Yang, Liuzhou Mao, Panqin Ma, Chiyu Jia, Karen Yuanting Tang, Xian Jun Loh, Yun‐Long Wu   +7 more
wiley   +1 more source