Results 191 to 200 of about 288,387 (304)

Captivated by Kinesin

Cytoskeleton, EarlyView.
ABSTRACT Few proteins have inspired as much curiosity as kinesin. Since its discovery 40 years ago, kinesin has become one of the best understood molecular machines in biology, yet it continues to reveal new questions about how cells organize and move their contents.
Ronald D. Vale
wiley   +1 more source

Aurora kinase B as a therapeutic target in HPV-induced cervical cancer: mechanisms and future perspectives. [PDF]

Front Oncol
Karnik M, Anantharaju PG, Sharma A, Sukocheva O, Tse E, Madhunapantula SV.   +5 more
europepmc   +1 more source

ACTIVE A and AURORA [PDF]

Preventive Cardiology, 2009
openaire   +2 more sources

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

Cytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith, Lauren A. Tauer, Randall H. Friedline, Xiaodi Hu, Duy Tran, Yangyi E. Luo, Nacima Hadjout‐Rabi, Elisabeth R. Barton, Jason K. Kim, Elizabeth J. Luna   +9 more
wiley   +1 more source

Dual Inhibition of TRIP13 and Aurora A Induces Mitotic DNA Damage and Concurrent Pyroptotic-Apoptotic Cell Death in Rb-Deficient Cancer Cells. [PDF]

Clin Cancer Res
Yapindi L, Ghosh S, Shen L, Diao L, Wang J, Johnson FM.   +5 more
europepmc   +1 more source

Effect of Magnetic Islands on Neoclassical Heat Diffusivity in a Global Tokamak Simulation

Contributions to Plasma Physics, EarlyView.
ABSTRACT Resonant magnetic perturbations (RMPs) alter magnetic field topology via island formation and can modify core transport in toroidal fusion devices. Using the global gyrokinetic particle‐in‐cell code XGC‐S, originally developed for stellarator geometries, we quantify how island topology affects neoclassical heat transport in a circular tokamak ...
Joseph X. Li, Toseo Moritaka, Ryutaro Kanno, Gakushi Kawamura, Robert Hager, C.‐S. Chang   +5 more
wiley   +1 more source

New Roles of Chk1 in Spindle Formation and Genome Integrity. [PDF]

Biology (Basel)
Balafouti S, Zachos G, Petsalaki E.
europepmc   +1 more source

High‐Dimensional Spectral Flow Cytometry Panel for Immunophenotypic Characterization of Fixed Whole Blood Samples

Cytometry Part A, EarlyView.
ABSTRACT Peripheral blood mononuclear cells (PBMCs) are commonly used for immune profiling in clinical research, but their isolation and cryopreservation present logistical challenges, particularly in settings with limited access to research facilities. To address this, we implemented a whole blood fixation protocol to preserve surface protein epitopes
Vaishnavi Parthasarathy, Alexander T. Heubeck, Tyanna Stuckey, Veronica Hernandez, Blessing Musgrove, Maia M. Bennett‐Boehm, Troy Torgerson, Peter Skene, Julian Reading   +8 more
wiley   +1 more source

FlowCytoMonitoR: An R‐Shiny Program for Advanced Monitoring Flow Cytometer Performance

Cytometry Part A, EarlyView.
ABSTRACT Flow cytometers are highly sensitive scientific instruments that need to be in optimal condition to provide accurate and reliable data. To ensure consistent performance, cytometer performance is regularly assessed by measuring standardized reference particles during a quality control (QC) measurement.
Britt Kolen, G. IJsbrand Reyneveld, Tom B. Kuipers, Marjolijn Hameetman, Hailiang Mei, Tamar Tak   +5 more
wiley   +1 more source

Simultaneous Transcatheter Aortic Valve Replacement and Endovascular Aneurysm Repair in a Patient With Peripheral Artery Disease Requiring Surgical Vascular Access: A Case Report. [PDF]

J Soc Cardiovasc Angiogr Interv
Pampori A, Radaideh Q, Banday W, Gupta R, Bajwa TK.   +4 more
europepmc   +1 more source