Results 231 to 240 of about 370,830 (302)

Ionome Dynamics in Grapevine Leaves. [PDF]

Plants (Basel)
Kováčik J, Vydra M, Husáková L, Piroutková M, Dresler S, Dekan M, Duchoň F.   +6 more
europepmc   +1 more source

Coupling Exponential Rolling Circle Amplification to Lateral Flow Devices for Point‐of‐Care Detection of Viral RNA

Angewandte Chemie, EarlyView.
A new exponential RCA (E‐RCA) system was developed and coupled to a toehold system for release of a bridging DNA, allowing for lateral flow detection. The E‐RCA method uses a secondary primer (P2) that binds RCA products (RCAP) to generate extended P2 products that can re‐prime a partially self‐complementary circular template, generating a complete ...
Amal Mathai, Monsur Ali, Yingfu Li, John D. Brennan   +3 more
wiley   +1 more source

Guidelines, Frameworks, and Trainings on Lived Experience and Caregiver Engagement in Research: Common Threads With Specific Considerations for Specific Subpopulations. [PDF]

Health Expect
Hawke LD, Burgé Luviano H, Payne K, Phi T, Monroe H, Putterman C, Hiebert M, Conway S, Hollingdrake E, Narajos A, Chiuccariello L.   +10 more
europepmc   +1 more source

Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron

Angewandte Chemie, EarlyView.
Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej, Arturo Rodríguez‐Banqueri, Danuta Mizgalska, Borys Szmigielski, Zuzanna Nowakowska, Małgorzata Benedyk‐Machaczka, Monika Bzowska, Katarzyna Mikruta, Juan Sebastián Ramírez‐Larrota, Chinanu Agunanne, Olivier Julien, Anthony J. O'Donoghue, Carsten Scavenius, Mario López‐Martín, Enrique Marcos, Łukasz Koziej, Sebastian Glatt, Pablo Guerra, Ulrich Eckhard, Jan Potempa, F. Xavier Gomis‐Rüth   +20 more
wiley   +1 more source

Atypical Condensation Domains Guide Discovery and Illuminate Biosynthesis of Myxoglucamides Featuring Vinyl‐Substituted, α‐Oxidized γ‐Amino Acids

Angewandte Chemie, EarlyView.
Genome mining of atypical condensation (C) domains leads to the discovery of myxoglucamides, glycolipopeptides featuring an unprecedented vinyl‐substituted, α‐oxidized γ‐amino acid. Biosynthetic studies reveal a discrete C‐domain‐like O‐acyltransferase, a β‐hydroxylation‐dependent chain‐extension checkpoint, and an unusual pathway for γ‐amino acid ...
Tingting Wang, Alexander Popoff, Maja Hunter, Guangzhi Dai, Ronald Garcia, Huixin Xu, Haowen Zhao, Asfandyar Sikandar, Liujie Huo, Rolf Müller, Chengzhang Fu   +10 more
wiley   +1 more source

Broad‐Spectrum, Cell Envelope‐Active Marinocyclin Antibiotics From a Coral‐Derived Bacterium Are Effective Against Colistin‐Resistant Bacteria

Angewandte Chemie, EarlyView.
Marinocyclins, polycationic macrocyclic depsipeptides, were discovered by genome mining from the marine coral‐derived bacterium Aquimarina megaterium. The compounds have broad‐spectrum activity against gram‐positive and gram‐negative ESKAPE bacteria.
Clara Chepkirui, Sandra Silva, Jan Straetener, Chandrashekhar Padhi, Tina Keller‐Costa, Tess Lamer, Laura Reinke, Heike Brötz‐Oesterhelt, Rodrigo Costa, Jörn Piel   +9 more
wiley   +1 more source

Building meaningful relationships through co-design: reflections from a participatory multi-year research partnership to create MedManageSCI. [PDF]

Front Health Serv
Cadel L, Chow A, Hitzig SL, McCarthy LM, Hahn-Goldberg S, Carvalho C, Ching E, Fiedorec S, Gateman M, Kaiser A, Kowalchuk A, Makim S, Mastrodimos K, Mo H, Raney P, El-Kotob R, Guilcher SJT.   +16 more
europepmc   +1 more source

A structured hands-on CSF diagnostic training module improves diagnostic knowledge in medical students: a prospective pre-post study. [PDF]

BMC Med Educ
Liu Y, Kottackal S, Hao W.
europepmc   +1 more source

Comparing behavioral cues of self- versus other-assessed authenticity using automated video interviews. [PDF]

Sci Rep
Liou G, Tay L.
europepmc   +1 more source