Results 31 to 40 of about 370,830 (302)
Authentic conditions for authentic assessment: Aligning task and assessment [PDF]
, 2006 Despite major discussion and consideration of authentic assessment through the 1990s, little progress appears to have been made towards its widespread adoption in higher education.
Herrington, J., Herrington, A.
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Frontiers in ChemistryBackgroundUlcerative colitis (UC) is a chronic inflammatory bowel disease driven by gut microbial dysbiosis and metabolic dysfunction. Matrine, a natural alkaloid with anti-inflammatory properties, shows therapeutic potential; however, its mechanisms ...
Linqi Su +10 more
doaj +1 more source
Authentic E-Learning in higher education: Design principles for authentic learning environments and tasks [PDF]
, 2006 With many learners failing to engage with didactic and outmoded instructional methods, and unwilling to use technology that simply replicates the one-way transfer of information from teacher to student, authentic learning designs have the potential to ...
Herrington, J.
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Calycosin ameliorates albuminuria in nephrotic syndrome by targeting Notch1/Snail pathway
BMC NephrologyBackground Heavy proteinuria is an important hallmark for kidney disease including nephrotic syndrome. Astragali Radix, a traditional Chinese herb, holds the potential to alleviate nephrotic syndrome; however, the underlying mechanism has not been ...
Xiaohong Ma, Binghe Guan, Linrong Pang
doaj +1 more source
Designing authentic activities for web-based courses [PDF]
, 2002 Influenced by constructivist philosophy and advances in technology, there is increasing interest in authentic activities as a basis for learning in both face-to-face and web-based courses.
Herrington, J.
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
npj Science of FoodEfforts in the filing and organisation of primary data, despite being a pillar of digital transformation, appear to be less pronounced when it comes to unstructured or text-based data.
Andreas Hofmann +2 more
doaj +1 more source
The Legal Category of Authenticity. Current Perspectives
Теория и практика судебной экспертизы, 2017 This overview focuses on the conceptualization of authenticity as a practical category that has always preoccupied those pondering the reality of the world as such, and aspiring to make sense of themselves and their purpose in this world.
O. A. Krestovnikov
doaj +1 more source