Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Correction to: Quality of Life of People with Mental Health Challenges and Problematic Substance Use while Engaged with an Exercise Physiology Service. [PDF]
Kugelman J +5 more
europepmc +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Bridging Medicine and Dentistry Through Clinical Pathology: A Call for Integration. [PDF]
Maruyama T.
europepmc +1 more source
Correction: Habitual video gaming predicts multitasking performance while the role of cognitive capacity remains inconclusive. [PDF]
Hilla Y, Stasch SM, Mack W.
europepmc +1 more source
Author Correction: Tectonic-astronomical interactions in shaping late Paleozoic climate and organic carbon burial. [PDF]
Wei R +7 more
europepmc +1 more source
Corrigendum to: Phentolamine rescue for glanular ischemia in the setting of inadvertent administration of high-dose 1:1,000 epinephrine to glans in distal hypospadias surgery [Urol Case Rep, (59), March 2025, 102941. PMID: 39925745]. [PDF]
Schulte V +3 more
europepmc +1 more source

