Results 241 to 250 of about 3,853,100 (308)

On the economic burden of alopecia areata in Romania. [PDF]

Front Health Serv
Olaru M, Tatu AL, Olteanu R, Lapadatu R, Vladescu C, Strilciuc S, Nicolescu AC.   +6 more
europepmc   +1 more source

Stimulation of OGG1 Enhances Oxidative DNA Damage Repair and Protects Against Acute Liver Failure by Acetaminophen

Advanced Science, EarlyView.
Chemical switching of OGG1 by CMM‐98 accelerates oxidative DNA damage repair and enhances hepatocyte resilience during acetaminophen‐induced acute liver injury. By promoting efficient processing of OGG1‐generated repair intermediates, CMM‐98 reduces oxidative damage, preserves cellular integrity, and protects against acute liver failure, identifying ...
Zhenjun Zhao, Rahul Upadhyay, Alice Eddershaw, Chenchen Wang, Yudong Zhao, Olov Wallner, Jinhye Ryu, Nayere Taebnia, Heather Gildie, Emma Scaletti‐Hutchinson, Jonathan R. Davies, Nicole Ziegler, Andreas Krämer, Samantha C. Robinson, Marek Varga, Karolina Singerova, Zuzanna Szaruga, Elisée Wiita, İrşil Güneş, Sheila S. David, Stefan Knapp, Aimo Kannt, Miguel de Vega, Pål Stenmark, Volker M Lauschke, Maurice Michel   +25 more
wiley   +1 more source

Coupled increases in pelagic fish productivity and export productivity during the Paleocene-Eocene Thermal Maximum. [PDF]

Nat Commun
Zhou X, Zhang R, Tsang MY, Li M, Yao W.
europepmc   +1 more source

CXCL3 Antagonism Reverses Systemic Antitumor Immune Memory Impairment Associated With High Tumor Burden and Sensitizes Anti‐PD‐1 Therapy

Advanced Science, EarlyView.
This study reveals that large tumors secrete more chemokine CXCL3, which recruits immunosuppressive neutrophils to the periphery, thereby impairing the activation and memory of systemic tumor‑reactive CD8+ T cells. CXCL3 antagonism restores systemic immune memory and enhances the antitumor efficacy of anti‑PD‑1 therapy, offering a potential strategy to
Ji Wang, Xinyu Tang, Zeju Li, Qi Qi, Chang Sun, Wen Sun, Weiya Zhang, Yue Yin, Ya Deng, Peiwen Ling, Yifan Xu, Guangshun Sun, Yi Ren, Hong Pan, Shui Wang, Wenbin Zhou   +15 more
wiley   +1 more source

Surgical paradox: Pen <i>vs</i> scalpel-an opinion review on reforming academic promotion. [PDF]

World J Methodol
Mahamid A.
europepmc   +1 more source

Versatile Microgel Platform for Intervertebral Disc Degeneration Therapy: Targeting Pericyte‐Mediated Fibrosis and Protecting Nucleus Pulposus Cells

Advanced Science, EarlyView.
The engineered MMS@TRP microgel enables targeted, acid‐responsive delivery of a miR‐21 inhibitor to pericytes. It effectively suppresses disc fibrosis by inhibiting TGF‐β signaling while protecting nucleus pulposus cells via sustained, antioxidant tannic acid release.
Fei Ma, Zhen Zhao, Chuan Guo, Yuheng Liu, Yu Wang, Dengbo Yao, Weiqiang Lan, Dejun Zhong, Chen Fan, Yao He, Mei Zhang, Qingquan Kong, Yunfeng Lin   +12 more
wiley   +1 more source

The response of wheat yield, water productivity, and partial factor productivity of nitrogen to straw return and biochar application: a global meta-analysis. [PDF]

Front Plant Sci
Yang Z, Chen W, Lu M, Ma P, Yu X, Li L, Wu S, Hu Y.   +7 more
europepmc   +1 more source

Reassessing the health-agriculture nexus: evidence from super-efficiency DEA and panel models in OECD countries. [PDF]

BMC Public Health
Selamzade F.
europepmc   +1 more source

Advancing Cardiovascular Nurse Practitioner and Physician Associate Workforce: Role for a Recruitment and Retention Program. [PDF]

JACC Case Rep
Severson S, Yeadon M, Booth-Kowalczyk M, Linderbaum J, Skov M.   +4 more
europepmc   +1 more source

Correction to "Resident and Migratory Falcons' Breeding Phenology and Productivity Respond Differently to Weather and Climate Change Across the Arctic". [PDF]

Glob Chang Biol
europepmc   +1 more source