Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
A corpus-based study on Chinese and American students' rhetorical moves and stance features in dissertation abstracts. [PDF]
Front Psychol, 2022 Liu Y, Hu X, Liu J.
europepmc +1 more source
Living Through the Looking Glass
, 2005 In Lewis Carroll’s (1871, 1992) well-known poem from Through the Looking Glass, “Jabberwocky”, nonsense words combine with known English words to create a whimsical effect appealing to readers of all ages. The words seem to gambol and dance in the ear as
Pennington, Rebecca E.
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
A Corpus Study of Lexical Bundles Used Differently in Dissertations Abstracts Produced by Chinese and American PhD Students of Linguistics. [PDF]
Front Psychol, 2022 Bao K, Liu M.
europepmc +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A Corpus Linguistics Approach to the Representation of Western Religious Beliefs in Ten Series of Chinese University English Language Teaching Textbooks. [PDF]
Front Psychol, 2021 Liu Y, Zhang LJ, Yang L.
europepmc +1 more source
Authorial stance in scientific writing: A cross-linguistic and cross-disciplinary study of markers of authorial stance-taking in linguistics, economics, and technology research articles written in English, Serbian, and German [PDF]
Across different languages and disciplines, authors use a variety of linguistic strategies to introduce their own voice into their academic texts. They do so, not only to report on their findings, but also to denote their agency and responsibility for the research overtly or covertly, to express certainty or possibility in the claims they are making ...
openaire +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source