Results 151 to 160 of about 34,842 (260)

Design, synthesis and activity evaluation of tetrahydroisoquinoline‐based programmed cell death ligand 1 inhibitors

Smart Molecules, EarlyView.
Based on a 3D‐quantitative structure‐activity relationship pharmacophore model, structural optimization of Y6 yielded Y7f. Mechanistic studies revealed that Y7f acted as a programmed death receptor 1/programmed cell death ligand 1 (PD‐L1) interaction inhibitor by inducing PD‐L1 dimerization. Y7f restored T‐cell function.
Menglin Yu, Sen Cai, Yanyan Pan, Heshuang Wang, Fengwu Zhang, Aiyu Ma, Shixuan Lv, Xiuhan Guo, Shisheng Wang, Qiling Song, Chunyan Ma, Shuai Wang, Li Zhang, Jian Wang, Qingwei Meng, Yueqing Li   +15 more
wiley   +1 more source

The relationship between aggression and authoritarianism

, 2013
The primary focus of the study was to find a positive correlation between right wing authoritarianism and anger, hostility, and aggression (verbal and physical).
Gonzalez, Jeremy B.
core  

Central Bank Digital Currencies, Financial Inclusion, and Privacy: A Normative Perspective

Southern Economic Journal, EarlyView.
ABSTRACT Central bank digital currencies (CBDCs) are a digital form of a nation's money, issued by its central bank. As opposed to other forms of digital money, such as electronic bank balances or cryptocurrencies, they are centrally managed legal tender.
Andrew Allison, Alexander William Salter
wiley   +1 more source

The Futures of Digital Democracy: Four Scenarios. [PDF]

Open Res Eur
Fuchs C, Museba J, Friesch K.
europepmc   +1 more source

Adding Realism to Theories of Taxpayer Compliance

Southern Economic Journal, EarlyView.
ABSTRACT Explaining why people pay taxes has not been a central focus in the many important contributions of Jim Cox. Even so, I argue here that his work has greatly affected the way that we think about taxpayer compliance, by adding both directly and indirectly much needed realism to the theories and the applications of compliance. These contributions
James Alm
wiley   +1 more source

Resisting Psychopathologies of Dominance and Authoritarianism: From Trumpian Dystopia to Better Tomorrows. [PDF]

J Psychiatr Ment Health Nurs
Haslam M, McKeown M.
europepmc   +1 more source

Emergency Response Capabilities of Institutions of Higher Education: A Case of a Developing Country

Safety Science and Technology, EarlyView.
This study justifies its significance by addressing crucial gaps in knowledge concerning emergency response capabilities in higher education institutions, focusing specifically on the KNUST; ranked as the best university for quality education (SDG 4) by Times Higher Education in 2023.
Lyndon N. A. Sackey, Bin U. Sadique, Janice Tetteh, Abena T. Twumasi, Ebuka B. Uwanda, Ebenezer E. Y. Amuah, Daniel K. O. Asamoah   +6 more
wiley   +1 more source

Support for authoritarianism and use of force by and against the federal government in the United States in mid-2025: findings from a nationally representative survey. [PDF]

Inj Epidemiol
Wintemute GJ, Crawford A, Tomsich EA, Wright MA, Shev AB, Tancredi DJ, Schleimer JP, Pear VA, Robinson SL.   +8 more
europepmc   +1 more source

Formation of Distance‐Based Orientation: Political Identity through Relational Positioning in Israel

Symbolic Interaction, EarlyView.
Distance‐based orientation describes how pejorative labels may serve as anchor points for political identity. Existing research on political labeling has largely emphasized stigmatization, overlooking how labels may acquire durability and orienting capacity without losing pejorative force. Drawing on publicly circulating discourse, we trace positioning
Tammar Friedman, Asaf Saadon
wiley   +1 more source

Public knowledge, stigma, and social acceptance toward mental illness in the Gulf region: a cross-sectional survey. [PDF]

Front Psychiatry
Alhamad H, Alsiri N, Alshehab M, Alenezi M, Alqallaf S.   +4 more
europepmc   +1 more source