Results 61 to 70 of about 133,319 (289)
NIOSH Authoritative Recommendations Program [PDF]
"The NIOSH Authoritative Recommendations Program seeks to maximize the impact and reach of science and policy across the spectrum of occupational hazards affecting workers in all industries" - NIOSHTIC-2NIOSHTIC no.
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This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
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Authoritative Scriptures and the Dead Sea Scrolls
The approach advocated in this article is the understanding of canon as authoritative literature that is binding for the Qumran community. The distinctive features of this approach are: authority is related to a community; the pesherite is central to the
Timothy H. Lim
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
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We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Authoritative\ua0Recommendations\ua0Program [2018]
The National Institute for Occupational Safety and Health (NIOSH) Authoritative Recommendations Program supports the scientific assessment, development, dissemination, and diffusion of NIOSH authoritative recommendations for assuring safe and healthy ...
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Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
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Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The canon, authoritative scriptures, and the scrolls
The Dead Sea Scrolls have shed light on the canonization of the Old Testament or Hebrew Bible in the Second Temple period. They provide us with exemplars of their biblical texts and how they used them in an authoritative manner. ‘The canon, authoritative
Timothy H. Lim
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