FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Digital religion and hybrid religious authority in algorithmically mediated environments. [PDF]
Front SociolAkhmetova A +4 more
europepmc +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
More Than a Role Dispute: Physician Associates and the Changing Grounds of Medical Authority. [PDF]
Sociol Health IllnAshley L.
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Efficacy, Effectiveness, and Efficiency of Nurse-Led Interventions: Insights From a Critical Systematic Review. [PDF]
Nurs InqFontanals-Jimenez A +2 more
europepmc +1 more source
Kansas Electric Transmission Authority 2014 Annual Report to the Governor and the Legislature
, 2015 January 12, 2015KETA was created in 2005 by enactment of HB 2263. Our mission is to ensure reliable operation of the electrical transmission system, diversify and expand the Kansas economy and facilitate consumption of Kansas energy through improvements ...
Kansas Electric Transmission Authority
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Beyond Role Expansion: Building Prepared, Empowered and Accountable Nurse Leaders for the HIV Response. [PDF]
HIV AIDS (Auckl)Manirafasha EN.
europepmc +1 more source
State of Connecticut Public Utilities Regulatory Authority; Public Utilities Regulatory Authority
, 2011 Updated irregularly; Began in 2011.; Title from home page (publisher's Web site, viewed July 6, 2011).; At head of title: State of Connecticut.; Harvested from the web on 7/7/11Official website of the Connecticut Public Utilities Regulatory Authority ...
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