Results 231 to 240 of about 3,580,734 (302)

Multi-event dynamic capture-recapture model for big data: Estimating undetected COVID-19 cases in British Columbia, Canada. [PDF]

Infect Dis Model
Olobatuyi K, Ma J, Brown P, Cowen LLE.
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

The fragile dialogue: communication barriers, authority and adaptive strategies in NICU parent-healthcare worker relationships. [PDF]

Front Sociol
Decataldo A, Lauritano G, Paleardi F.
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Professional nurses' perspectives on the influence of Ideal Clinic status on patient care quality in eThekwini, South Africa. [PDF]

Health SA
Mazibuko NN, Ngxongo TSP, Sokhela DG.
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Assessment of compliance with good review practices by medicine assessors within the Zambia medicines regulatory authority. [PDF]

Front Med (Lausanne)
Chisha CS, Leigh S, Siyanga M, McAuslane N, Walker S.   +4 more
europepmc   +1 more source

Building Trust in Governmental and Educational Authorities in Adolescence: A Comparison of Early, Middle, and Late Adolescents in Four European Countries. [PDF]

J Youth Adolesc
Brojac J, Šerek J, Forstmeier S, Đorđević A, Ilić V, Padoan E, Štěpánková L, Möbert A, Masling A, Marangoni F, Fikrlova J.   +10 more
europepmc   +1 more source

Understanding rice production stagnation in the Philippines: Regional evidence and development implications. [PDF]

PLoS One
Bartelet HA, Prodigalidad AJD, Dy JS, Manzano JGN.   +3 more
europepmc   +1 more source