Results 131 to 140 of about 254,717 (266)

Rethinking expertise in artificial intelligence ethics for global health. [PDF]

Int Health
Irfan B, Sirvent R.
europepmc   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Challenges in hybrid management in healthcare: a study of the interplay between divisional managers and clinical directors in a decentralized healthcare organization in Sweden. [PDF]

BMC Health Serv Res
Ohrling M.
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Software Applications Ecosystem for Authority Control

, 2015
Leandro Tabares Martín, Félix Óscar Fernández Peña, Amed Abel Leiva Mederos, Marc Goovaerts, Dailién Calzadilla Reyes, Wilbert Alberto Ruano Álvarez   +5 more
openalex   +2 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Risk-driven or authority-based? Unraveling public policy compliance during the pandemic in China. [PDF]

Front Public Health
Zhang H, Luo C, Yang C, Ouyang Y, Deng X.   +4 more
europepmc   +1 more source

The Influence of Delegation of Authority and Management Control on the Effectiveness of Managerial Decision-Making in the Arab Pharmaceutical Manufacturing Company Limited in Al-Salt City in Jordan

, 2019
Mohammed A. Abu Rumman, Amani Abdelhafeeth Alzeyadat   +1 more
openalex   +2 more sources

Arrangement of Authority for Investigators of the National Drug and Food Control Agency (BPOM) in Law Enforcement in the Field of Drugs, Food and Beverages [PDF]

, 2020
Surung Malem Karo Sekali, Sudarsono Sudarsono, I Nyoman Nurjaya, Abdul Rachmad Budiono   +3 more
openalex   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source