Results 21 to 30 of about 691,001 (359)

Elevated rates of autism, other neurodevelopmental and psychiatric diagnoses, and autistic traits in transgender and gender-diverse individuals

Nature Communications, 2020
It is unclear if rates of autism and other neurodevelopmental and psychiatric diagnoses are elevated in transgender and gender-diverse individuals compared to cisgender individuals.
Varun Warrier, David M. Greenberg, Elizabeth Weir, Clara Buckingham, Paula Smith, Meng-Chuan Lai, Carrie Allison, Simon Baron-Cohen   +7 more
doaj   +1 more source

Integrated systems analysis reveals a molecular network underlying autism spectrum disorders. [PDF]

, 2014
Autism is a complex disease whose etiology remains elusive. We integrated previously and newly generated data and developed a systems framework involving the interactome, gene expression and genome sequencing to identify a protein interaction module with
Euskirchen, Ghia, Hallmayer, Joachim, Li, Jingjing, Ma, Zhihai, Shi, Minyi, Snyder, Michael, Urban, Alexander, Zhao, Shuchun, Ziskin, Jennifer   +8 more
core   +1 more source

A comparative study of autistic and non-autistic women’s experience of motherhood

Molecular Autism, 2020
Background Autism is a lifelong neurodevelopmental difference and disability, yet there is limited research examining parenting in autistic mothers. Objective To explore autistic mothers’ experience of the perinatal period and parenthood.
A. L. Pohl, S. K. Crockford, M. Blakemore, C. Allison, S. Baron-Cohen   +4 more
doaj   +1 more source

Evidence against the “normalization” prediction of the early brain overgrowth hypothesis of autism

Molecular Autism, 2020
Background The frequently cited Early Overgrowth Hypothesis of autism spectrum disorder (ASD) postulates that there is overgrowth of the brain in the first 2 years of life, which is followed by a period of arrested growth leading to normalized brain ...
Lisa D. Yankowitz, John D. Herrington, Benjamin E. Yerys, Joseph A. Pereira, Juhi Pandey, Robert T. Schultz   +5 more
doaj   +1 more source

Knowing me, knowing you: perspectives on awareness in autism [PDF]

, 2015
Purpose: This paper raises important questions from the different perspectives on autism research that arose from a seminar on autism and technology, held as part of an ESRC-funded series on innovative technologies for autism.
Brosnan, Mark, Good, Judith, Parsons, Sarah, Yuill, Nicola   +3 more
core   +1 more source

The Autism‐Spectrum Quotient in siblings of people with Autism [PDF]

Autism Research, 2016
This study measures the distribution of autistic traits, using the autism‐spectrum quotient (AQ), in siblings of individuals with autism spectrum conditions (ASC). Total AQ scores, along with AQ subscales, were collected from child, adolescent and adult controls, siblings, and volunteers with ASC using one of the three age‐appropriate versions of the ...
Ruzich, Emily, Allison, Carrie, Smith, Paula, Ring, Howard, Auyeung, Bonnie, Baron-Cohen, Simon   +5 more
openaire   +5 more sources

Conditional Pten knockout in parvalbumin- or somatostatin-positive neurons sufficiently leads to autism-related behavioral phenotypes

Molecular Brain, 2021
Disrupted GABAergic neurons have been extensively described in brain tissues from individuals with autism spectrum disorder (ASD) and animal models for ASD.
Sangyep Shin, Andrea Santi, Shiyong Huang   +2 more
doaj   +1 more source

The prevalence and incidence of mental ill-health in adults with autism and intellectual disabilities [PDF]

, 2008
The prevalence, and incidence, of mental ill-health in adults with intellectual disabilities and autism were compared with the whole population with intellectual disabilities, and with controls, matched individually for age, gender, ability-level, and ...
A. V. Brereton, Alison Jackson, B. Holden, C. Lord, C. Morgan, C. W. McGrother, Craig A. Melville, D. G. Allen, D. Mantry, Dipali Mantry, E. A. Bradley, E. A. Bradley, E. Billstedt, E. Smiley, E. Tsakanikos, E. Tsakanikos, Elita Smiley, F. Tyrer, G. Baird, G. Dawson, H. Leonard, H. Schrojenstein Lantman-de Valk van, H. W. M. Kwok, J. Bertrand, J. Hill, J. K. Kern, J. L. Matson, J. L. Matson, J. Robertson, Janet Finlayson, Jill Morrison, K. McClintock, L. Lecavalier, L. Wing, Linda Allan, M Yeargin-Allsopp, M. E. Stewart, M. G. Aman, M. Ghaziuddin, M. Ghaziuddin, M. Hotopf, M. M. Konstantareas, M. Wullink, N. Holmes, National Initiative: Autism Screening, Assessment, P. A. Filipek, P. Sturmey, P. W. Davidson, R. A. Collacott, R. Didden, R. Didden, R. Farmer, R. M. Reese, S. -A. Cooper, S. -A. Cooper, S. A. Borthwick-Duffy, S. A. Cooper, S. A. Cooper, S. Bhaumik, S. Chakrabarti, S. Chakrabarti, S. Deb, S. Moss, Sally-Ann Cooper, Scottish Intercollegiate Guideline Network, T. D. Cook, World Health Organisation, World Health Organisation   +67 more
core   +1 more source

Elevated fetal steroidogenic activity in autism [PDF]

, 2014
Autism affects males more than females, giving rise to the idea that the influence of steroid hormones on early fetal brain development may be one important early biological risk factor.
Abdallah, M W, Auyeung, B, Baron-Cohen, S, Chakrabarti, B, Cohen, A S, Hougaard, D M, Lombardo, M V, Melgaard, L, Nørgaard-Pedersen, B, Ruta, L   +9 more
core   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source