Results 61 to 70 of about 691,001 (359)

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

A genome-first study of sex chromosome aneuploidies provides evidence of Y chromosome dosage effects on autism risk

Nature Communications
A female protective effect has long been postulated as the primary explanation for the four-fold increase of autism spectrum disorder (ASD) diagnoses in males versus females.
Alexander S. F. Berry, Brenda M. Finucane, Scott M. Myers, Lauren K. Walsh, John M. Seibert, Christa Lese Martin, David H. Ledbetter, Matthew T. Oetjens   +7 more
doaj   +1 more source

Linguistic markers of autism in girls: evidence of a “blended phenotype” during storytelling

Molecular Autism, 2019
Background Narrative abilities are linked to social impairment in autism spectrum disorder (ASD), such that reductions in words about cognitive processes (e.g., think, know) are thought to reflect underlying deficits in social cognition, including Theory
Jaclin Boorse, Meredith Cola, Samantha Plate, Lisa Yankowitz, Juhi Pandey, Robert T. Schultz, Julia Parish-Morris   +6 more
doaj   +1 more source

Large scale validation of an early-age eye-tracking biomarker of an autism spectrum disorder subtype

Scientific Reports, 2022
Few clinically validated biomarkers of ASD exist which can rapidly, accurately, and objectively identify autism during the first years of life and be used to support optimized treatment outcomes and advances in precision medicine.
Teresa H. Wen, Amanda Cheng, Charlene Andreason, Javad Zahiri, Yaqiong Xiao, Ronghui Xu, Bokan Bao, Eric Courchesne, Cynthia Carter Barnes, Steven J. Arias, Karen Pierce   +10 more
doaj   +1 more source

Exploring face perception in disorders of development: evidence from Williams syndrome and autism [PDF]

, 2008
Individuals with Williams syndrome (WS) and autism are characterized by different social phenotypes but have been said to show similar atypicalities of face-processing style.
Baron-Cohen, Baron-Cohen, Bellugi, Bellugi, Bellugi, Boucher, Brothers, Bruce, Bruce, Calder, Castelli, Deborah M. Riby, Deruelle, Deruelle, Dunn, Frigerio, Frith, Gepner, Gwyneth Doherty-Sneddon, Haxby, Hefter, Johnson, Jones, Karmiloff-Smith, Karmiloff-Smith, Karmiloff-Smith, Klin, Kylliäinen, Lopéz, Meyer-Lindenberg, Morris, Mottron, Peeters, Plesa-Skwerer, Raven, Reiss, Rutter, Schopler, Searcy, Singh, Strømme, Tager-Flusberg, Tassabehji, Teunisse, Teunisse, Thomas, Tranel, Vicki Bruce, Wing, Zebrowitz   +49 more
core   +1 more source

Refractory Status Epilepticus Treated With Bilateral Pulvinar Deep Brain Stimulation—A Case Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT New‐onset refractory status epilepticus (NORSE) arises without an identifiable cause or prior epilepsy history, with a 16%–27% mortality rate and significant long‐term neurological sequelae. Neuromodulation such as deep brain stimulation (DBS) targeting the anterior and centromedian thalamic nuclei has shown promise when the traditional ...
Mengxuan Tang, Amerta Bai, Felipe Rodridgues Marques Ferreira, Sandipan Pati, Thaddeus Walczak, Benjamin Miller, Oladi Bentho, Thomas Henry, Ilo Leppik, Minoo Shams, Zhiyi Sha, Zachary Sanger, Theoden I. Netoff, Thomas Lisko, Anant Naik, Robert McGovern III, Sima Patel   +16 more
wiley   +1 more source

Effects of oxytocin administration on salivary sex hormone levels in autistic and neurotypical women

Molecular Autism, 2020
Background Oxytocin administration, which may be of therapeutic value for individuals with social difficulties, is likely to affect endogenous levels of other socially relevant hormones.
Tanya L. Procyshyn, Michael V. Lombardo, Meng-Chuan Lai, Bonnie Auyeung, Sarah K. Crockford, J Deakin, S. Soubramanian, A Sule, Simon Baron-Cohen, Richard A. I. Bethlehem   +9 more
doaj   +1 more source

The prevalence of autism spectrum disorders in China: A comprehensive meta-analysis [PDF]

, 2018
There are conflicting prevalence estimates of autism spectrum disorders (ASDs) in mainland China (China thereafter). This study is a comprehensive meta-analysis of the pooled prevalence of ASDs in the general population in China.
Cao, Xiao-Lan, Hou, Cai-Lan, Jia, Fu-Jun, Lu, Jian-Ping, Lu, Li, Ng, Chee H, Ungvari, Gabor S, Wang, Fei, Wang, Shi-Bin, Xiang, Yu-Tao, Zhang, Ling   +10 more
core   +2 more sources

Epigenetics and Autism [PDF]

Autism Research and Treatment, 2013
This review identifies mechanisms for altering DNA-histone interactions of cell chromatin to upregulate or downregulate gene expression that could serve as epigenetic targets for therapeutic interventions in autism. DNA methyltransferases (DNMTs) can phosphorylate histone H3 at T6.
Tafari Mbadiwe, Richard M. Millis
openaire   +2 more sources

Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes

Advanced Science, EarlyView.
This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang, Meiyun Wang, Peng Zhang, Jingliang Cheng, Longjiang Zhang, Wenzhen Zhu, Shijun Qiu, Zuojun Geng, Guangbin Cui, Yongqiang Yu, Weihua Liao, Xi‐Nian Zuo, Hui Zhang, Bo Gao, Xiaojun Xu, Tong Han, Zhenwei Yao, Quan Zhang, Feng Liu, Qiang Xu, Jiayuan Xu, Jilian Fu, Nana Liu, Yuan Ji, Jie Tang, Lining Guo, Mengge Liu, Xiaoxiao Xiao, Xiaoxuan Liu, Wei Li, Caihong Wang, Wei Wei, Dapeng Shi, Su Lui, Zhihan Yan, Feng Chen, Jing Zhang, Wen Shen, Yanwei Miao, Dawei Wang, Jia‐Hong Gao, Yunjun Yang, Kai Xu, Junfang Xian, Bing Zhang, Xiaochu Zhang, Zhaoxiang Ye, Le Yu, Wen Qin, Meng Liang, Chunshui Yu, the CHIMGEN Consortium   +51 more
wiley   +1 more source