Results 141 to 150 of about 543,651 (394)

Astrocytes and Microglia and Their Potential Link with Autism Spectrum Disorders

open access: yesFrontiers in Cellular Neuroscience, 2016
The cellular mechanism(s) underlying autism spectrum disorders (ASDs) are not fully understood although it has been shown that various genetic and environmental factors contribute to their etiology.
F. Petrelli, L. Pucci, P. Bezzi
semanticscholar   +1 more source

Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Yaqiang Hu et al. engineered a pathogenic Sec16a mutant mouse model using CRISPR/Cas9 technology. They observed that the Sec16a mutant mice displayed diminished learning and memory capabilities, along with a limb‐clasping phenotype upon tail suspension.
Yaqiang Hu   +6 more
wiley   +1 more source

“…”: Prostate Cancer Patients’ Evaluations of Their Diagnosis and Treatment Experiences

open access: yesAmerican Journal of Men's Health, 2018
The objective of the current study was to identify the patient-perceived “worst aspects” of their diagnostic and treatment processes for prostate cancer (PCa) so as to inform targeted interventions aimed at reducing patient anxiety and depression.
Christopher F Sharpley   +2 more
doaj   +1 more source

Late Pregnancy Antiseizure Medication Exposure and Offspring Neurodevelopmental Risk: A Multi‐Child Cohort Study

open access: yesAnnals of Neurology, EarlyView.
Objective Antiseizure medication (ASM) use during pregnancy has increased over the past decade. However, evidence linking prenatal ASM exposure to neurodevelopmental disorders (NDDs) in offspring remains inconsistent. This study evaluated whether prenatal ASM exposure increases the risk of NDDs in children.
Odile Sheehy   +13 more
wiley   +1 more source

Auditory Discrimination and Auditory Sensory Behaviours in Autism Spectrum Disorders [PDF]

open access: yes, 2009
It has been hypothesised that auditory processing may be enhanced in autism spectrum disorders (ASD). We tested auditory discrimination ability in 72 adolescents with ASD (39 childhood autism; 33 other ASD) and 57 IQ and age-matched controls, assessing ...
Charman, Tony, Jones, Catherine
core   +1 more source

Electroencephalography in Autism Spectrum Disorder

open access: yesJournal of Clinical Medicine
Background/Objectives: Electroencephalography (EEG) has been widely used to differentiate individuals with autism spectrum disorder (ASD) and co-occurring conditions, particularly epilepsy. However, the relationship between EEG abnormalities and core features of ASD remains unclear.
Magdalena Hankus   +4 more
openaire   +2 more sources

Harnessing the Neurobiology of Empathy and Compassion to Alleviate Burnout in Neurology

open access: yesAnnals of Neurology, EarlyView.
The neurologist cares for patients with complex chronic conditions that compromise their wellbeing. Many such disorders are poorly understood. Whereas for some, effective symptomatic treatments exist, for most we lack an understanding of the molecular and cellular bases for disease pathogenesis needed for discovering disease‐modifying treatments ...
Fadel Zeidan   +2 more
wiley   +1 more source

Exploring Alexithymia, Uncertainty, Anxious Arousal, and Social Anxiety as Mediators of the Relationship Between Sensory Processing Differences and Restricted and Repetitive Behaviors in Autistic Adults

open access: yesAutism Research, EarlyView.
ABSTRACT Restricted and repetitive behaviors (RRB) are associated with sensory processing (SP) differences for autistic people, and are thought to be a coping strategy to help manage the sensory environment. Previous work shows that, for autistic people, alexithymia, intolerance of uncertainty (IU), and anxiety mediate the relationship between SP ...
Heather L. Moore   +6 more
wiley   +1 more source

Successful passive sentence comprehension among Danish adolescents with autism spectrum disorders

open access: yesAutism and Developmental Language Impairments, 2018
Background and aims Language abilities vary greatly across children with autism spectrum disorders (ASD). In the present study, we investigate passive sentence comprehension, which has been underexplored among individuals with autism spectrum disorders ...
Kristine Jensen de López   +2 more
doaj   +1 more source

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