Autism-associated SNPs in the clock genes _npas2_, _per1_ and the homeobox gene _en2_ alter DNA sequences that show characteristics of microRNA genes. [PDF]
, 2008 Intronic single nucleotide polymorphisms (SNPs) in the clock genes _npas2_ and _per1_ and the homeobox gene _en2_ are reported to be associated with autism.
Brad Nicholas +3 more
core +1 more source
Deficits in Temporal Processing Associated with Autistic Disorder
Frontiers in Integrative Neuroscience, 2011 Currently idiopathic autism is typically diagnosed according to an observational assessment of certain behavioral, social, and cognitive tendencies across dimensions of language, social interaction, imaginative play, and restricted or repetitive ...
Melissa J. Allman
semanticscholar +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Smith‐Kingsmore syndrome (SKS) is a rare autosomal dominant condition characterized by neurodevelopmental differences, macrocephaly/megalencephaly, describable facial features, sleep–wake abnormalities, hyperphagia, and overgrowth. SKS is caused by pathogenic gain‐of‐function variants in MTOR which lead to hyperactivation of the mTOR pathway ...
Carolyn R. Raski, Carlos E. Prada
wiley +1 more source
Association between heavy metals exposure (cadmium, lead, arsenic, mercury) and child autistic disorder: a systematic review and meta-analysis. [PDF]
Front Pediatr, 2023 Ding M, Shi S, Qie S, Li J, Xi X.
europepmc +1 more source
Appraisal of Gene Expression‐Based Classifiers for Neuropsychiatric Disorders: A Meta‐Regression
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT A substantial body of research examines the potential of gene‐expression‐based biomarkers for diagnosing and selecting treatments for neuropsychiatric disorders, yet no clear consensus has been reached regarding the influence of controllable factors such as study design and model selection on the performance of gene‐expression‐based ...
Ali Razavi +6 more
wiley +1 more source
Quality of life of mothers of children with autistic disorder
Al-Azhar Assiut Medical JournalBackground and aim Quality of life (QoL) assessment for families of autistic children has become a crucial research topic. Purpose of this study was to evaluate the QoL of mothers of children diagnosed with autistic disorder.
Amira M.M. Hamed +3 more
doaj +1 more source
Autism and Communication: A Phenomenology of Parents’ Perspectives [PDF]
, 2018 Autism spectrum disorders (ASD) are characterized by language impairments and are often treated with a variety of communication interventions. In addition to these interventions, the parents of autistic children have to learn how to care for and ...
Sargent, Zoe
core +1 more source
Potential therapeutic use of the ketogenic diet in autism spectrum disorders. [PDF]
, 2014 The ketogenic diet (KGD) has been recognized as an effective treatment for individuals with glucose transporter 1 (GLUT1) and pyruvate dehydrogenase (PDH) deficiencies as well as with epilepsy.
Dueñas, Nadia +2 more
core +1 more source
Dental Trauma in Children with Autistic Disorder: A Retrospective Study. [PDF]
Biomed Res Int, 2021 Marra PM +9 more
europepmc +1 more source
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition that is increasingly linked to immune dysfunction and neuroinflammation. Regulatory T cells (Tregs), which are crucial in maintaining immune homeostasis, have been implicated in the pathogenesis of ASD.
Zuqing Nie +9 more
wiley +1 more source