Results 71 to 80 of about 174,454 (348)
Autistic trait interactions underlie sex-dependent facial recognition abilities in the normal population [PDF]
Autistic face processing difficulties are either uniquely social or due to a piecemeal cognitive "style". Co-morbidity of social deficits and piecemeal cognition in autism makes teasing apart these accounts difficult.
Barsky, AR +4 more
core +2 more sources
Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes
This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang +51 more
wiley +1 more source
Lack of action–sentence compatibility effect in non-clinical individuals with high autistic traits
IntroductionPatients with autism spectrum disorder (ASD) exhibit atypical responses to language use and comprehension. Recently, various degrees of primary autistic symptoms have been reported in the general population.
Keisuke Irie +5 more
doaj +1 more source
Autistic Spectrum Disorder: Behaviour Therapy, Relationship Therapy and Play; A Combined Future? [PDF]
This review aims to look at the research undertaken in each of the two branches of Autistic Spectrum Disorder therapy, comparing and evaluating their individual successes and looking for an integrated way forward including the role of play and ...
MacDonald, Natalie
core
Prominent autistic traits and subthreshold bipolar/mixed features of depression in severe anorexia nervosa [PDF]
Autistic traits are associated with a burdensome clinical presentation of anorexia nervosa (AN), as is AN with concurrent depression. The aim of the present study was to explore the intertwined association between complex psychopathology combining ...
Anastasia, Annalisa +6 more
core +1 more source
Single‐nucleus RNA sequencing of mid‐gestation brains from fetuses with nonsyndromic cleft lip and palate reveals major disruptions in cell composition, cell‐to‐cell signaling, and gene regulation. The transcription factor MEF2C is identified as a central regulator of these changes and shows that lowering MEF2C impairs synapse formation, linking cleft ...
Liu‐Lin Xiong +19 more
wiley +1 more source
NEAT1 Promotes Epileptogenesis in Tuberous Sclerosis Complex
The primary neurological manifestations of tuberous sclerosis complex (TSC) are intractable epilepsy and intellectual disability. NEAT1 is differentially expressed in TSC‐related epilepsy and influences neuronal excitability by regulating the PI3K/AKT/mTOR signaling pathway.
Suhui Kuang +8 more
wiley +1 more source
Multiscale Construction, Evaluation, and Application of Organoids
Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma +5 more
wiley +1 more source
Pragmatic disorders and their social impact [PDF]
Pragmatic disorders in children and adults have been the focus of clinical investigations for approximately 40 years. In that time, clinicians and researchers have established a diverse range of pragmatic phenomena that are disrupted in these disorders ...
Cummings, L
core +1 more source
Parabiosis, Assembloids, Organoids (PAO)
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong +5 more
wiley +1 more source

