Results 71 to 80 of about 178,874 (344)
European Psychiatry, 2023 Introduction Autism spectrum disorder (ASD) is a heterogenous groups of neurodevelopmental conditions characterized by difficulties in social communication and the presence of restricted interests and repetitive behaviors.
L. Fusar-Poli +4 more
doaj +1 more source
Autistic Spectrum Disorder: Behaviour Therapy, Relationship Therapy and Play; A Combined Future? [PDF]
, 2014 This review aims to look at the research undertaken in each of the two branches of Autistic Spectrum Disorder therapy, comparing and evaluating their individual successes and looking for an integrated way forward including the role of play and ...
MacDonald, Natalie
core
Advanced Science, EarlyView.Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi +5 more
wiley +1 more source
A systematic review of people with autism spectrum disorder and the Criminal Justice System [PDF]
, 2014 This paper provides a systemic review of the available literature on people with autism spectrum disorder (ASD) in the criminal justice system (CJS). The review considers two main types of study: those that examined the prevalence of people with ASD in ...
King, C., Murphy, Glynis H.
core +1 more source
The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia
Advanced Science, EarlyView.The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo +3 more
wiley +1 more source
A proposed framework of an interactive semi-virtual environment for enhanced education of children with autism spectrum disorders [PDF]
, 2009 Education of people with special needs has recently been considered as a key element in the field of medical education. Recent development in the area of information and communication technologies may enable development of collaborative interactive ...
Bamidis, Panagiotis D. +4 more
core +1 more source
The Microbiota Shapes Central Nervous System Myelination in Early Life
Advanced Science, EarlyView.Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch +13 more
wiley +1 more source
Modeling Autistic Features in Animals [PDF]
, 2011 A variety of features of autism can be simulated in rodents, including the core behavioral hallmarks of stereotyped and repetitive behaviors, and deficits in social interaction and communication.
Patterson, Paul H.
core +1 more source
Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling
Advanced Science, EarlyView.Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu +20 more
wiley +1 more source
Autism = Death: The social and medical impact of a catastrophic medical model of autistic spectrum disorders [PDF]
, 2008 This discussion interrogates the continuing impact of the pervasive and persistent usage of debilitating metaphors perpetuating ‘historical’ superstitions, myths and beliefs surrounding disability.
Waltz, Mitzi
core +1 more source