Results 81 to 90 of about 174,454 (348)
Advanced Science, EarlyView.Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu +14 more
wiley +1 more source
Describing Multidomain Health Outcomes in Autistic Children in the ECHO Program
JAACAP OpenObjective: The goal of this study is to characterize health outcomes across 3 domains—overall well-being, behavioral health, and physical health—in a large sample of autistic and non-autistic children and adolescents in the Environmental influences on ...
Elizabeth A. Kaplan-Kahn, PhD +25 more
doaj +1 more source
A systematic review of people with autism spectrum disorder and the Criminal Justice System [PDF]
, 2014 This paper provides a systemic review of the available literature on people with autism spectrum disorder (ASD) in the criminal justice system (CJS). The review considers two main types of study: those that examined the prevalence of people with ASD in ...
King, C., Murphy, Glynis H.
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Advanced Science, EarlyView.This study describes derivation of two distinct mechanosensory subpopulations from human pluripotent stem cells using a transcription factor mediated approach. Of significance, functional interrogation of induced mechanosensory subtypes reveal their unique responses to mechanical stimulation in the absence of end‐organs.
Amy J. Hulme +12 more
wiley +1 more source
No association between autistic traits and contextual influences on eye-movements during reading [PDF]
PeerJ, 2014 Individuals with autism spectrum disorders are claimed to show a local cognitive bias, termed “weak central coherence”, which manifests in a reduced influence of contextual information on linguistic processing.
Nathan Caruana, Jon Brock
doaj +2 more sources
The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia
Advanced Science, EarlyView.The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo +3 more
wiley +1 more source
Jurnal Pendidikan dan Kebudayaan, 2011 The goal of this research is to prove that the application of sensorimotor training can improve writing skills and the writing in Autistic Spectrum Disorder (ASD) children, the research question posed is: Does the application of sensory motor training ...
Musjafak Assjari, Eva Siti Sopariah
doaj +1 more source
The autism spectrum as a source of cognitive and cultural diversity [PDF]
, 2011 Individual differences in perception and in social cognition are products of both biology and cultural experience. Many of the same differences that typify autism when they occur in extremes also underlie normal human cognitive variation when they occur ...
Belmonte, MK
core
Knowing me, knowing you: perspectives on awareness in autism [PDF]
, 2015 Purpose: This paper raises important questions from the different perspectives on autism research that arose from a seminar on autism and technology, held as part of an ESRC-funded series on innovative technologies for autism.
Brosnan, Mark +3 more
core +1 more source
Advanced Science, EarlyView.MS436 competitively binds to the BD1 domain of Brd4, thereby suppressing Brd4 induced degradation of tight junction proteins via the Rnf43‐Fzd4‐β‐catenin signaling pathway. Consequently, this attenuation of degradation reduces blood‐brain barrier leakage, leading to an improved overall prognosis after stroke.
Chenxiao Li +10 more
wiley +1 more source