Results 121 to 130 of about 155,668 (297)

Longitudinal Phenotypic Trajectories in GNAO1‐Related Disorders: Defining Disease Progression and Clinical Profiles

Annals of Neurology, EarlyView.
Objective Pathogenic variants in GNAO1 cause a spectrum of epilepsy, movement disorders, and developmental impairment. Clinical heterogeneity complicates prognosis and therapeutic development. We present the first longitudinal natural history study of GNAO1‐related disorders (GNAO1‐RD) to delineate phenotypic trajectories. Methods Sixty‐six individuals
Jana Domínguez‐Carral, Ana María Domínguez Cobo, Sol Balsells, Anna Aguilar‐Ros, Chu‐Ting Chang, William G. Ludlam, Kathryn Yang, Katerina Bernardi, Micaela Chinigioli, Ainara Salazar‐Villacorta, Veronica Di Pisa, Nuria Lamagrande‐Casanova, Elena González‐Alguacil, Beatriz De la Casa‐Fages, Akihisa Okumura, Josefina Rodríguez, Ayush Agarwal, Daniela Muñoz‐Chesta, Carolina Reynoso‐Osnayo, Amy Lin, Brahim Tabarki, Jobaida Parvin, Adolfo Alberto Gallo, Andreia Forno, Fabian Maass, Johnny Montiel Blanco, Salomé Nasif, Elizabeth Jennions, Jorge Luis Ramón‐Gómez, Helene Verhelst, Juan José Nieto Barceló, Dunja Čokolić Petrović, Luz Victoria García Ruiz, Christoph van Riesen, Paulo Rego Sousa, Maria del Pilar Massaro Sanchez, Husnea Ara Khan, Wejdan Hakami, Jennifer Friedman, Iván Espinoza‐Quinteros, Monica Troncoso, Divyani Garg, Micaela Pauni, Hirokazu Kurahashi, María Concepción Miranda‐Herrero, Anna Duat‐Rodriguez, Luca Soliani, Manju A. Kurian, Angeles Schteinschnaider, Siddharth Srivastava, Darius Ebrahimi‐Fakhari, Kirill A. Martemyanov, Juan Darío Ortigoza‐Escobar   +52 more
wiley   +1 more source

Challenges Faced by Teachers When Teaching Learners with Autistic Spectrum Disorder in Special Schools in the Capricorn District, Limpopo Province, South Africa

Proceedings
Background: Teachers of learners with Autistic Spectrum Disorder (ASD) encounter various challenges that impact learners’ educational outcomes [...]
Keorapetse L. Ralebapa, Mokoko P. Kekana
doaj   +1 more source

Photocaged Oxytocin and Vasopressin Probes to Decipher Neuropeptide Signalling With High Spatiotemporal Resolution

Angewandte Chemie International Edition, EarlyView.
Novel and biocompatible photoactivatable oxytocin and vasopressin probes, utilising state‐of‐the‐art photocages, remain inactive in the dark. Light exposure facilitates rapid spatiotemporal receptor activation and phospholipase C (PLC)‐mediated downstream signalling. Figure created in https://BioRender.com.
Konstantin Raabe, Predrag Kalaba, Xuan Ling Hilary Yong, Greta Crudeli, Sarah Melzer, Erik Keimpema, Victor Anggono, Markus Muttenthaler   +7 more
wiley   +1 more source

SOCIAL-PRAGMATIC COMMUNICATION IN WOMEN WITH AUTISM SPECTRUM DISORDER: A MULTIPLE CASE STUDY [PDF]

, 2017
Autism spectrum disorder (ASD) is identified much later and less often in females than in males. Some researchers suspect that a different set of characteristics of ASD in females may not be consistent with the more established and widely recognized ...
Ryder, Lacey W
core   +1 more source

Labor Epidural Analgesia and Autism Spectrum Disorder in Offspring: A Population‐Based Case–Control Study

Autism Research, EarlyView.
ABSTRACT While the immediate benefits of labor epidural analgesia (LEA) are well established, recent studies have raised concerns about possible associations with autism spectrum disorder (ASD). Therefore, we examined the association between LEA and ASD in offspring.
Taniqua T. Ingol, Jessie K. Edwards, Mollie E. Wood, Chantel L. Martin, Gabriel S. Dichter, Keith Feldman, Alan C. Kinlaw, Julie L. Daniels   +7 more
wiley   +1 more source

Vocabulary of Autistic Preschool Children With Limited Language: Alignment With Early Word Inventories

Autism Research, EarlyView.
ABSTRACT There is a critical need to understand the early vocabulary of young children with autism who have limited language, defined in this study as producing fewer than 20 different spontaneous and functional spoken or augmented words, to better inform educational targets and vocabulary selection for spoken as well as augmentative and alternative ...
Eunji Kong, Yitong Jiang, Marina Crain, Wenjing Bao, Lynne Levato, Wendy Shih, Connie Kasari, Stephanie Shire   +7 more
wiley   +1 more source

Health related quality of life in children with autism spectrum disorder in Bangladesh

IMC Journal of Medical Science, 2017
Background and objective: Autism spectrum disorder (ASD) is considered as an emerging problem in our socioeconomic context. The objectives of this study were to compare the health related quality of life of children with autism spectrum disorder to that ...
Farhana safa, Md. Nazrul Islam
doaj  

Parenting Stress and Stressful Life Events Among Caregivers of Toddler Siblings of Autistic and Non‐Autistic Children

Autism Research, EarlyView.
ABSTRACT This study measured experiences of parenting stress and stressful life events in caregivers of families with a toddler who has either an autistic or non‐autistic older sibling(s). Caregivers of toddlers (12–18 months old) with older autistic siblings (Sibs‐autism; n = 58) and toddlers with older non‐autistic siblings (Sibs‐NA; n = 46 ...
Jennifer E. Magnuson, Lucy S. King, Jacob I. Feldman, S. Madison Clark, Grace Pulliam, Kacie Dunham‐Carr, Alexandra Golden, Bahar Keçeli‐ Kaysılı, Kathryn L. Humphreys, Tiffany G. Woynaroski   +9 more
wiley   +1 more source

Adverse Childhood Experiences in Autistic and Neurotypical Girls

Autism Research, EarlyView.
ABSTRACT Adverse childhood experiences (ACEs) are potentially traumatic, life‐altering events that occur in childhood with long‐term negative physical and/or mental health outcomes. Previous research, while limited and largely focused on males, suggests children with autism spectrum disorder (ASD) are at higher risk of experiencing ACEs than typically ...
Jon Ebert, Rachael A. Muscatello, Trey McGonigle, Simon Vandekar, Blythe A. Corbett   +4 more
wiley   +1 more source

Autistic Traits as Predictors of Increased Obsessive–Compulsive Disorder Severity: The Role of Inflexibility and Communication Impairment

Brain Sciences
Due to similar manifestations, some authors have proposed a potential correlation between autism spectrum disorder (ASD) and obsessive–compulsive disorder (OCD).
Liliana Dell’Osso, Benedetta Nardi, Chiara Bonelli, Giulia Amatori, Maria Alessandra Pereyra, Enrico Massimetti, Ivan Mirko Cremone, Stefano Pini, Barbara Carpita   +8 more
doaj   +1 more source