Results 41 to 50 of about 155,668 (297)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
The evolving diagnostic and genetic landscapes of autism spectrum disorder
Frontiers in Genetics, 2016 The autism spectrum disorders (ASD) are a heterogeneous set of neurodevelopmental syndromes defined by impairments in verbal and non-verbal communication, restricted social interaction, and the presence of stereotyped patterns of behavior.
Mark Nicholas Ziats, Owen Murray Rennert
doaj +1 more source
Autistic Spectrum Disorder: Behaviour Therapy, Relationship Therapy and Play; A Combined Future? [PDF]
, 2014 This review aims to look at the research undertaken in each of the two branches of Autistic Spectrum Disorder therapy, comparing and evaluating their individual successes and looking for an integrated way forward including the role of play and ...
MacDonald, Natalie
core
Memory, learning and language in autism spectrum disorder [PDF]
, 2018 Background and aims: The ‘dual-systems’ model of language acquisition has been used by Ullman and colleagues to explain patterns of strength and weakness in the language of higher-functioning people with autism spectrum disorder (ASD).
Bodison S. +9 more
core +2 more sources
Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1
Advanced Science, EarlyView.Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency +19 more
wiley +1 more source
Relationship between autistic traits and social functioning in healthy individuals
Neuropsychopharmacology Reports, 2022 Aim Social functioning is influenced by various factors. Autistic traits could be one of the factors that affect social functioning. Methods In the present study, the relationship between autistic traits and social functioning among 755 healthy ...
Yuria Demizu +9 more
doaj +1 more source
Revista Brasileira de Ginecologia e Obstetrícia, 2021 Objective To analyze the scientific production regarding maternal folic acid (FA) supplementation and its relationship with autistic spectrum disorder (ASD).
Adalberto Cruz Sampaio +10 more
doaj +1 more source
Parents' future visions for their autistic transition-age youth: hopes and expectations [PDF]
, 2018 Researchers have documented that young adults with autism spectrum disorder have poor outcomes in employment, post-secondary education, social participation, independent living, and community participation. There is a need to further explore contributing
Chen, Jennifer +2 more
core +1 more source
Paving the Way to Elucidate Hg's Role in Tumorigenesis
Advanced Science, EarlyView.Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li +10 more
wiley +1 more source
Iranian Journal of Psychiatry, 2018 Objective: This study aimed to identify autistic like traits in relatives of patients with schizophrenia and autism spectrum disorder. Method: causal-comparative research design was utilized.
Zeynab Khanjani +3 more
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