Visual impairment prevention by early detection of diabetic retinopathy based on stacked auto-encoder. [PDF]
Sci RepAlmas S +6 more
europepmc +1 more source
Using EfficientNet-B7 (CNN), Variational Auto Encoder (VAE) and Siamese Twins' Networks to Evaluate Human Exercises as Super Objects in a TSSCI Images. [PDF]
J Pers Med, 2023 Segal Y, Hadar O, Lhotska L.
europepmc +1 more source
Plant‐Derived Melatonin Inhibits Bacterial Virulence via CpxA/R Two‐Component System
Advanced Science, EarlyView.Plant‐derived melatonin is sensed by CpxAE48/T51, which inhibits the phosphorylation cascade transmission from CpxAH240 to CpxRD52, resulting in the inhibition of DNA‐binding capacity of CpxR and subsequent T3SS genes expression in Pst DC3000. ABSTRACT In defending against pathogens, plants deploy diverse secondary metabolites and signaling molecules ...
Jin‐Wei Wei +7 more
wiley +1 more source
Post‐Translational Regulation of CD8+ T Cell Fate and Dysfunction in Tumor Immunity
Advanced Science, EarlyView.This review delineates how post‐translational modifications (PTMs) function as a central regulatory interface governing CD8+ T cell activation, differentiation, persistence, and exhaustion in antitumor immunity. By integrating antigenic, metabolic, and microenvironmental cues, diverse PTM programs coordinate transcriptional and chromatin states that ...
Zihao Zhou +8 more
wiley +1 more source
Electrocardiogram analysis for cardiac arrhythmia classification and prediction through self attention based auto encoder. [PDF]
Sci RepShah A +5 more
europepmc +1 more source
Investigating Phase Separation in Genome Folding via Multiscale Computational Modeling
Advanced Science, EarlyView.Phase separation is emerging as a multiscale organizing principle of genome folding across scales, from nucleosomes and transcriptional condensates to chromatin domains and nuclear compartments. By integrating physics‐based simulations with data‐driven inference, computational modeling now links molecular interactions to nuclear architecture and points
Jiahu Tang +3 more
wiley +1 more source
Author Correction: An efficient enhanced stacked auto encoder assisted optimized deep neural network for forecasting Dry Eye Disease. [PDF]
Sci RepRajan S, Ponnan S.
europepmc +1 more source
Advanced Science, EarlyView.A novel transcriptional module involving CsYABBY3 and CsAS1 is identified to regulate cannabinoid biosynthesis and trichome development. These factors mutually activate each other and form a protein complex via a conserved residue, acting synergistically to amplify metabolic flux through a coordinate feed‐forward mechanism.
Xuewen Zhu +18 more
wiley +1 more source
Auto encoder-based defense mechanism against popular adversarial attacks in deep learning. [PDF]
PLoS OneAshraf SN, Siddiqi R, Farooq H.
europepmc +1 more source
Advanced Science, EarlyView.This study designs a targeted nanocomposite (ct@HMCF‐Dex) that responds to acidic infection microenvironments, releasing components which amplify oxidative stress. It disrupts bacterial redox balance, chelates metals to sustain lipid peroxidation, and synergistically induces cuproptosis/ferroptosis‐like death.
Zehui Xiao +6 more
wiley +1 more source