Results 151 to 160 of about 912,674 (282)

The Landscape of Long Non‐Coding RNAs Provides Insights Into the Domestication and Improvement of Pear Fruit

open access: yesAdvanced Science, Volume 13, Issue 62, 9 November 2026.
This study reveals that long non‐coding RNAs represent important regulatory components underlying pear domestication and improvement. Integrative multi‐omics analyses identify selected lncRNAs associated with fruit traits, while functional validation uncovers a lignin‐related lncRNA, lncRNA‐pys, that promotes lignin accumulation.
Bobo Song   +9 more
wiley   +1 more source

ClusterApp to visualize, organize, and navigate metabolomics data. [PDF]

open access: yesPLoS Comput Biol
Figueiredo da Costa VH   +6 more
europepmc   +1 more source

IFI27 and BAX are Essential for GSDME‐Mediated Myeloma Cell Pyroptosis

open access: yesAdvanced Science, EarlyView.
The proposed model of GSDME‐mediated MM cell pyroptosis modulated by IFI27 and BAX. IFI27 is downregulated in MM cells. Upon pyroptotic stimulation, such as DOX or ETO treatment, IFI27 is induced, therefore liberating BAX from BCL‐2 ❶. BAX is then recruited to mitochondria and forms homo‐oligomeric channels in OMM, therefore leading to cytochrome C ...
Yaoli Cui   +12 more
wiley   +1 more source

Nanosecond phase ordering in ultra-large spin Hall nano-oscillator lattices for unconventional computing. [PDF]

open access: yesNat Nanotechnol
Behera N   +7 more
europepmc   +1 more source

Open‐Shell Conjugated Polymers Enable Photothermoelectric Conversion and Detection of Short‐Wave Infrared Light

open access: yesAdvanced Science, Volume 13, Issue 62, 9 November 2026.
Efficient conversion and detection of short‐wave infrared (SWIR) photons are becoming increasingly important for emerging photonic and energy technologies. Here, we report an organic photothermoelectric device based on an open‐shell conjugated polymer that enables SWIR energy conversion and photon detection via the photothermoelectric effect.
Guan‐Lin Chen   +5 more
wiley   +1 more source

Klotho‐Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A

open access: yesAdvanced Science, EarlyView.
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang   +6 more
wiley   +1 more source

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

open access: yesAdvanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu   +7 more
wiley   +1 more source

China's Low‐Carbon Energy Transition Over the Past Two Decades: Experiences and Implications

open access: yesAdvanced Science, EarlyView.
China's low‐carbon energy transition features a brief decline and subsequent rebound in coal consumption, alongside the rapid expansion of renewable energy. This study develops a stage‐based analytical framework to explain this evolution from the perspectives of economic development, energy security, and environmental sustainability, revealing how ...
Yu Liu   +3 more
wiley   +1 more source

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