Results 221 to 230 of about 763,556 (317)

Association between coronavirus disease 2019 and new-onset autoimmune diseases during the early phase of the pandemic. [PDF]

PLoS One
Park JH, Lee MT, Jung SY, Choi ST, Choi SH.   +4 more
europepmc   +1 more source

A 3D In Vitro Model of the Human Hepatobiliary Junction

Advanced Science, EarlyView.
A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield, Katarzyna A. Grzelak, Katie Katsuyama, Vardhman Kumar, Bess M. Miller, Joa Yun, Jesse Kirkpatrick, David Mankus, Margaret E. Bisher, Abigail K.R. Lytton‐Jean, Z. Gordon Jiang, David D. Lee, Christopher S. Chen, Sangeeta N. Bhatia   +13 more
wiley   +1 more source

Long-term follow-up of autoimmune polyendocrine syndrome type 1 in Norway.

J Clin Endocrinol Metab
Kucuka I, Wolff ASB, Breivik L, Sjøgren T, Bratland E, Grytaas M, Lima K, Jørgensen AP, Nermoen I, Bakke Å, Singsås H, Svendsen M, Finnes TE, Nedrebø BG, Haug T, Grimnes G, Rensvik ML, Gjerde CG, Marthinussen MC, Øksnes M, Oftedal BE, Husebye ES.   +21 more
europepmc   +1 more source

Limited penetrance of dominantly inherited AIRE variants in a population-based cohort. [PDF]

Hum Mol Genet
Ramchand SN, Leech JM, Sharp LN, Bonfield G, Luckett AM, Weedon MN, Patel KA, Hawkes G, Johnson MB.   +8 more
europepmc   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

MAGa: Monoclonal Autoimmune Gammopathies. [PDF]

Cancers (Basel)
Torres S, Wheeler SE, Shurin MR.
europepmc   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Potential stratification of TAFRO syndrome by anti-SS-A antibodies status and therapeutic response to rituximab. [PDF]

RMD Open
Suzuki T, Yamada S, Toriumi K, Kono M, Tsuchiya H, Fujio K.   +5 more
europepmc   +1 more source