Results 241 to 250 of about 9,605,298 (318)
This study introduces an in situ assembly of fluorogenic RNA approach for screening natural anti‐liver fibrosis compounds and dynamic visualization of endogenous COL1A1 mRNA in live cells. It offers a simple, cost‐effective approach of visualizing RNA dynamics and conducting drug screening in live cells, presenting a significant potential for the ...
Rui Bai+6 more
wiley +1 more source
Down Syndrome and Autoimmune Disease. [PDF]
Hom B+7 more
europepmc +1 more source
This study revealed that adiponectin facilitates the therapeutic efficiency of thrombopoietic agents by stimulating the membrane trafficking of c‐Mpl in MKs, which provides a point for ITP therapy. Moreover, a novel c‐Mpl trafficking mechanism based on the Myosin‐9/Rab6A complex is constructed. These findings provide new insights into the applicability
Xin Zhao+8 more
wiley +1 more source
Raising Suspicion of Thrombotic Thrombocytopenic Purpura in a Patient With a Pre-existing Autoimmune Disease. [PDF]
Murugan NL, Mensah R, Singh A.
europepmc +1 more source
Schwann cells may facilitate intracranial plaque progression via neurovascular remodelingcting with vascular smooth muscle cells in atherosclerotic plaques, with the SPP1 ‐ ITGB1 signaling axis mediating this interaction as a novel mechanism. Abstract Intracranial atherosclerosis (ICAS), a common cause of ischemic stroke, remains a therapeutic ...
Zijue Wang+10 more
wiley +1 more source
Follicular helper- and peripheral helper-like T cells drive autoimmune disease in human immune system mice. [PDF]
Khosravi-Maharlooei M+11 more
europepmc +1 more source
Autophagy in autoimmune disease
Zhen Yang, J. Goronzy, C. Weyand
semanticscholar +1 more source
Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen+7 more
wiley +1 more source