Results 111 to 120 of about 386,064 (216)

Type 1 Diabetes and Other Autoimmune Diseases—Epidemiology, Pathophysiology and Screening

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
Individuals with type 1 diabetes exhibit significantly increased prevalence of additional autoimmune diseases. Epidemiological, familial and mechanistic evidence indicates frequent polyautoimmunity and shared genetic and environmental drivers. Coexistence complicates clinical management, and autoantibody‐based detection often identifies preclinical ...
George J. Kahaly, Thomas Forst, Monika Kellerer, Stefanie Lanzinger, René D. Rötzer, Matthias Schott, Petra‐Maria Schumm‐Draeger   +6 more
wiley   +1 more source

The Updated Sydney System: Classification and Grading of Gastritis as the Basis of Diagnosis and Treatment

Canadian Journal of Gastroenterology, 2001
In recent years, the importance of the histological diagnosis of gastritis on the basis of routinely obtained antral and corpus biopsies has increased enormously, which is owed not least of all to the discovery of Helicobacter pylori. The introduction of
Manfred Stolte, Alexander Meining
doaj   +1 more source

Relative efficacy of GLP‐1 and GLP‐1/GIP receptor agonists in the prevention of alcohol‐use disorders using a target trial emulation approach

Diabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 137-150, January 2026.
Abstract Aims There is growing evidence that the GLP‐1 system is implicated in alcohol and other substance use disorders, and that GLP‐1‐based therapies may have therapeutic relevance in alcohol use disorder (AUD). We aimed to determine the impact of GLP‐1 based therapies on incident AUDs in a real‐world setting in patients with T2D.
Alex E. Henney, David R. Riley, Megan Heague, Carl A. Roberts, Theresa J. Hydes, Matthew Anson, David M. Hughes, Uazman Alam, Daniel J. Cuthbertson   +8 more
wiley   +1 more source

DNA Checkpoint and Repair Factors Are Nuclear Sensors for Intracellular Organelle Stresses-Inflammations and Cancers Can Have High Genomic Risks. [PDF]

, 2018
Under inflammatory conditions, inflammatory cells release reactive oxygen species (ROS) and reactive nitrogen species (RNS) which cause DNA damage. If not appropriately repaired, DNA damage leads to gene mutations and genomic instability.
Chen, Hongping, Choi, Eric T., Cueto, Ramon, Drosatos, Konstantinos, Fu, Hangfei, Nanayakkara, Gayani K, Park, Joon Y., Qin, Xuebin, Shao, Lijian, Shao, Ying, Sheng, Haitao, Sun, Jianxin, Sun, Yu, Wang, Hong, Wang, Luqiao, Wu, Na, Yang, Qian, Yang, William Y, Yang, Wuping, Yang, Xiaofeng, Zeng, Huihong, Zhu, Qingxian   +21 more
core   +2 more sources

Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives

Advanced Photonics Research, Volume 6, Issue 12, December 2025.
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka, Lenka Vaňková, Josef Sýkora, Věra Křížková, Jan Schwarz, Petr Bouř   +5 more
wiley   +1 more source

Pituitary hyperplasia mimicking macroadenoma associated with primary hypothyroidism in a patient with selective L-thyroxine malabsorption [PDF]

, 2017
We present the case of a 29-year-old woman who developed a severe hypothyroidism induced by a thyroxine malabsorption and a secondary pituitary hyperplasia.
Romanelli, Francesco, Sansone, Andrea, Sansone, Massimiliano, Tedone, Radha, Vena, Walter   +4 more
core   +1 more source

Microbial risk factors of cardiovascular and cerebrovascular diseases: potential therapeutic options [PDF]

, 2008
Infection and inflammation may have a crucial role in the pathogenesis of atherosclerosis. This hypothesis is supported by an increasing number of reports on the interaction between chronic infection, inflammation, and atherogenesis.
Abbas, M.A., Comi, G, Corea, F, Fawi, G, Galantucci, S, Guenther, A, Kwan, Joseph W.   +6 more
core   +1 more source

Transforming Pharmacovigilance With Pharmacogenomics: Toward Personalized Risk Management

Clinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1286-1296, December 2025.
Pharmacovigilance is a critical component of medication safety. Despite rigorous evaluation of new drugs during clinical trials, some adverse effects might only be identified once pharmaceuticals are used by a larger population for a longer duration.
Claire Spahn, Nanase Toda, Blaine Groat, Omar Aimer, Sara Rogers, Akinyemi Oni‐Orisan, Andrew Monte, Nancy Hakooz, on behalf of the Pharmacogenomics Global Research Network (PGRN) Publications Committee   +8 more
wiley   +1 more source

Two Cases of White Globe Appearance in Autoimmune Atrophic Gastritis

Case Reports in Gastrointestinal Medicine, 2018
In this report, we described two patients with white globe appearance in autoimmune atrophic gastritis. Endoscopy revealed multiple white substances in the stomach in both cases.
Masaya Iwamuro, Takehiro Tanaka, Hiromitsu Kanzaki, Seiji Kawano, Yoshiro Kawahara, Hiroyuki Okada   +5 more
doaj   +1 more source

Helicobacter pylori Eradication in Patients with Immune Thrombocytopenic Purpura: A Review and the Role of Biogeography [PDF]

, 2015
Idiopathic thrombocytopenic purpura (ITP) is typically a diagnosis of exclusion, assigned by clinicians after ruling out other identifiable etiologies. Since a report by Gasbarrini et al.
Beck, Paul L., Davis, Nicholas K., Fox, James G, Frydman, Galit   +3 more
core   +1 more source