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Immunopathogenesis, loss of T cell tolerance and genetics of autoimmune gastritis
Over the past 10 years experimental autoimmune gastritis has been established as a highly defined model of organ-specific autoimmunity. Autoimmune gastritis represents one of the few autoimmune diseases in which the causative autoantigens, namely the ...
Pablo Silveira +2 more
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Occurrence and Risk Factors for Autoimmune Thyroid Disease in Patients with Atrophic Body Gastritis
Purpose: To investigate the occurrence of and risk factors for autoimmune thyroid disease in atrophic body gastritis patients. Methods: Cross-sectional study on 401 consecutive outpatients with atrophic body gastritis.
Bruno Annibale +2 more
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Rat Experimental Autoimmune Gastritis Model
Immunological Investigations, 2023Autoimmune gastritis (AIG) is an autoimmune disease of the stomach characterized by the destruction of the oxyntic mucosa, which stops producing acid and becomes both functionally and morphologically atrophic. The pathogenic mechanisms behind the disease are still poorly understood. There is no early diagnosis and specific AIG therapy. To elucidate the
Liubov, Beduleva +5 more
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Autoimmune Atrophic Gastritis With Hypergastrinemia
Southern Medical Journal, 1976Elevation in fasting serum gastrin levels was found in three patients being evaluated for persistent upper abdominal pain without radiographic evidence of peptic ulcer disease. Fiberoptic endoscopy of the upper gastrointestinal tract in each patient revealed characteristic changes of chronic atrophic gastritis.
J D, Reinhardt +2 more
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Reversing the Autoimmune Condition: Experience with Experimental Autoimmune Gastritis
International Reviews of Immunology, 2005Autoimmune diseases remain a significant health problem in our society, despite the best efforts to understand and treat these conditions. Current clinical treatments are aimed at alleviating the consequences of these diseases, with limited prospects for cure.
Frank, Alderuccio +4 more
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Diagnosis and classification of autoimmune gastritis
Autoimmunity Reviews, 2014Autoimmune gastritis is a silent and highly prevalent disease that only becomes clinically manifested with progression to corpus atrophy and development of iron deficient or B12-deficient (pernicious) anaemia. Autoimmune gastritis is associated with autoimmune thyroiditis and type 1 diabetes mellitus.
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Morphological characteristics of autoimmune gastritis
Russian Journal of Archive of PathologyObjective. Detailed study of the morphological characteristics of autoimmune gastritis (AIG), assessment of the possibilities and prospects for morphological diagnosis of this disease. Material and methods. The study included 63 patients with AIG and 25 patients with chronic atrophic gastritis, who were examined in the clinics of Sechenov University ...
A.S. Tertychnyy +4 more
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Review of autoimmune metaplastic atrophic gastritis
Gastrointestinal Endoscopy, 2013SUMMARY The clinical goal of managing AMAG is to identifydysplastic or malignant lesions of the stomach as well as toensure the proper management of vitamin B 12 deficiencyto prevent the hematologic and neurologic adverse eventsof pernicious anemia. The testing algorithms for diagnos-ing pernicious anemia may not always apply to the diag-nosis of early ...
Jason Y, Park +2 more
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The challenging diagnosis of autoimmune atrophic gastritis
Scandinavian Journal of Gastroenterology, 2016Sir,We read with interest the article by Zhang et al. investigating 320 patients who were diagnosed with autoimmune atrophic gastritis (AAG) within a large cohort of 97,341 Chinese patients referre...
LENTI, MARCO VINCENZO +4 more
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Cutting Edge Issues in Autoimmune Gastritis
Clinical Reviews in Allergy & Immunology, 2010Autoimmune gastritis is the outcome of a pathological CD4 T cell-mediated autoimmune response directed against the gastric H/K-ATPase. Silent initially, the gastric lesion becomes manifest in humans by the development of megaloblastic pernicious anemia arising from vitamin B12 deficiency.
Ban-Hock, Toh +3 more
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