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Autoimmune hemolytic anemia

The Indian Journal of Pediatrics, 1998
Immune hemolytic anemia can be either isoimmune or autoimmune. Autoimmune hemolytic anemias (AIHA) consist of group of disorders whose common characteristics are the presence of an antibody which in turn causes short red blood cell (RBC) life. The rate and site of hemolysis and hence the clinical manifestations depends on the type of antibody attached ...
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Autoimmune Hemolytic Anemia

Medical Clinics of North America, 2017
Autoimmune hemolytic anemia is an acquired autoimmune disorder resulting in the production of antibodies directed against red blood cell antigens causing shortened erythrocyte survival. The disorders can present as a primary disorder (idiopathic) or secondary to other autoimmune disorders, malignancies, or infections.
Howard A, Liebman, Ilene C, Weitz
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Autoimmune hemolytic anemia

The Indian Journal of Pediatrics, 2008
To study the clinico-hematological profile and treatment outcome in children suffering from auto immune hemolytic anemia (AIHA).Twelve children were diagnosed with auto immune hemolytic anemia over a period of four years. Direct antiglobulin test was positive in all the cases.
V, Gupta, J, Shukla, B D, Bhatia
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Autoimmune hemolytic anemia in adults: primary risk factors and diagnostic procedures

Expert Review of Hematology, 2020
Introduction Autoimmune hemolytic anemia (AIHA) is due to autoantibodies against erythrocytes that may arise either because of primary tolerance breakage or along with several associated conditions, including genetic predispositions, congenital syndromes,
W. Barcellini, J. Giannotta, B. Fattizzo
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Autoimmune Pathogenesis and Autoimmune Hemolytic Anemia

Seminars in Hematology, 2005
Autoimmune hemolytic anemia (AIHA) is an autoimmune disorder in which autoantibodies are directed against an individual's own red blood cells (RBCs), leading to enhanced clearance through Fc receptor (FcR)-mediated phagocytosis. Although there is a large literature relating to clinical aspects of AIHA, relatively little work addresses how IgG ...
John W, Semple, John, Freedman
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Autoimmune hemolytic anemia: A history*

Transfusion Medicine Reviews, 2000
UTOIMMUNE HEMOLYTIC anemia (AIHA) is an acquired immunoIogic disease in which the patient's red blood cells (RBCs) are selectively attacked and destroyed (hemolyzed) by autoantibodies produced by the patient's own immune system. These patients generally display the common symptoms of anemia: weakness, pallor, fatigue, and jaundice.
P, Mack, J, Freedman
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Reticulocytopenia in Autoimmune Hemolytic Anemia

Blood, 1956
Abstract 1. In a series of 57 cases of autoimmune hemolytic anemia it was found that 25 or 44 per cent had a relative reticulocytopenia at times of hemolytic crisis. The mortality rate in this group was significantly higher than in those who showed a reticulocyte response consistent with the severity of anemia.
W H, CROSBY, H, RAPPAPORT
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Autoimmune Hemolytic Anemia

Pediatric Clinics of North America, 1980
In autoimmune hemolytic anemia, individuals produce antibodies directed against one of their own erythrocyte membrane antigens. The hemolysis in autoimmune hemolytic anemia is most commonly extravascular rather than intravascular, and the liver and spleen play a major role in the clearance of the antibody-coated cells.
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Autoimmune hemolytic anemia

Human Pathology, 1983
Nowhere in the management of patients with autoimmune hemolytic anemias is the communication between clinician and laboratory personnel more important than in regard to blood transfusion. A clinical decision that blood transfusion is necessary must be tempered by the knowledge that transfusion has a greater-than-usual risk in this setting, both because
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Autoimmune Hemolytic Anemia

Hospital Practice, 1985
Rh and ABO incompatibilities, drug reactions, and lupus are a few of the many causes of autoimmune hemolytic anemia. Among the determinants of autoimmunity involved are the class of the antibody, the biochemical composition of the antigen, the distribution of the antigen on the erythrocyte membrane, and the effector cells and molecules that are ...
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