Results 51 to 60 of about 30,364 (243)
American Journal of Hematology, EarlyView.ABSTRACT Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a
Bruno Fattizzo +38 more
wiley +1 more source
Autoimmune Hemolytic Anemia After Relapse of Chronic Myeloid Leukemia: A Case Report
Clinical Medicine Insights: Blood Disorders, 2019 Autoimmune hemolytic anemia is one of the differential diagnoses for anemia in patients with lymphoproliferative neoplasia, such as chronic lymphocytic leukemia, who experience sudden drop in hemoglobin.
Tahseen Hamamyh, Mohamed A Yassin
doaj +1 more source
Current Opinion in Immunology, 1994 Autoimmune hemolytic anemia (AHA) is characterized by the production of Coombs' antibodies, which are responsible for the destruction of red blood cells (RBCs). Analysis of both monoclonal anti-RBC autoantibodies derived from autoimmune New Zealand black mice and transgenic mice expressing a pathogenic IgM anti-RBC autoantibody has considerably ...
openaire +3 more sources
Antilymphoid antibody preconditioning and tacrolimus monotherapy for pediatric kidney transplantation [PDF]
, 2006 Objective: Heavy post-transplant immunosuppression may contribute to long-term immunosuppression dependence by subverting tolerogenic mechanisms; thus, we sought to determine if this undesirable consequence could be mitigated by pretransplant lymphoid ...
Abhay N. Vats +52 more
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective This study aimed to investigate the mechanisms of immune dysregulation in a pediatric patient with monogenic lupus driven by IKZF1 haploinsufficiency. Methods Peripheral immune cells from a patient with IKZF1 haploinsufficiency, patients with lupus with no currently known genetic mutations, and healthy controls were analyzed using single‐cell
Qi Zheng +6 more
wiley +1 more source
Haematologica, 2012 Background Interleukin-17A is the signature cytokine of the Th17 subset and drives inflammatory pathology, but its relevance to autoantibody-mediated diseases is unclear.
Andrew M. Hall +6 more
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Objective High‐intensity conditioning autologous hematopoietic stem cell transplantation (AHSCT) is standard of care for patients with advanced systemic sclerosis (SSc). The role of reduced‐intensity conditioning (RIC) before AHSCT in this population remains unclear.
Yonatan Lean +4 more
wiley +1 more source
Clinical Case Reports, 2022 Warm autoimmune hemolytic anemia (AIHA) is a hematologic disorder with an incidence of 1–3 per 105 individuals/year. Patients with systemic lupus erythematosus (SLE) develop AIHA in 3% of adult cases and 14% of pediatric cases.
Lake R. Crawford, Natalia Neparidze
doaj +1 more source
Autoimmune Hemolytic Anemia with Autoimmune Hypothyroidism: A Case Report
Journal of Nepal Medical Association, 2023 Autoimmune hemolytic anaemia is a relatively rare disorder caused by autoantibodies directed against self-red blood cells. Though autoimmune thyroid disease is associated with other autoimmune diseases, only a few cases of Hashimoto's thyroiditis with ...
Prakriti Karki +4 more
doaj +1 more source
ANK1 and EPB41 Variants and The Risk of Steroid‐Induced Osteonecrosis
Arthritis &Rheumatology, Accepted Article.Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen +21 more
wiley +1 more source