Results 1 to 10 of about 941,535 (195)
New England Journal of Medicine, 1996 Autoimmune hepatitis is an inflammatory liver disease in which the immune system is believed to orchestrate an immune attack onto the liver cell. Current knowledge suggests that both T helper 1 (TH1) and TH2 programmes are involved in the generation of the liver damage.
Edward L Krawitt, E L Krawitt
exaly +14 more sources
Journal of Hepatology, 2022 Autoimmune hepatitis (AIH) has been well characterized and codified through the development of diagnostic criteria. These criteria have been adapted and simplified and are widely used in clinical practice. However, there is a need to update and precisely
, George Dalekos, Michael Trauner
exaly +2 more sources
Jornal De Pediatria, 2019 Objective: This large study with a long‐term follow‐up aimed to evaluate the clinical presentation, laboratory findings, histological profile, treatments, and outcomes of children and adolescents with autoimmune hepatitis. Methods: The medical records of
Alexandre Rodrigues Ferreira +2 more
exaly +5 more sources
Nature Reviews Gastroenterology and Hepatology, 2011 Autoimmune hepatitis was one of the first liver diseases for which an effective treatment was developed and the benefit proven by randomized controlled trials. Nonetheless, both the diagnosis and the treatment of autoimmune hepatitis remain full of challenges.
Diego Vergani +2 more
exaly +3 more sources
JHEP Reports, 2019 Background & Aims Treatment options remain limited for patients with autoimmune hepatitis (AIH), while there are still concerns over the consequences of long-term corticosteroid use.
David Adams +2 more
exaly +2 more sources
Management of refractory autoimmune hepatitis with rituximab: a case series [PDF]
Journal of Medical Case ReportsBackground and aims Most patients with autoimmune hepatitis respond to the standard of care of prednisolone in combination with a thiopurine, or a second line of mycophenolate mofetil or tacrolimus.
Nicholas M. Batt +3 more
doaj +2 more sources
Late-onset combined immunodeficiency and bone marrow failure in severe autoimmune hepatitis: a case report [PDF]
Journal of Medical Case ReportsBackground Late-onset combined immunodeficiency ( is a rare primary immunodeficiency characterized by hypogammaglobulinemia, T-cell lymphopenia, and susceptibility to opportunistic infections.
Feriel Sahbani +7 more
doaj +2 more sources
Diagnosis and management of autoimmune hepatitis
British medical journal, 2023 Autoimmune hepatitis is an inflammatory disease of the liver of unknown cause that may progress to liver cirrhosis and end stage liver failure if diagnosis is overlooked and treatment delayed.
L. Muratori, A. Lohse, M. Lenzi
semanticscholar +2 more sources
Best Practice & Research Clinical Gastroenterology, 2006 Autoimmune hepatitis (AIH) was the first chronic liver disease in which remission was achieved by immunosuppression. Prognosis is poor when left untreated. Since the original description in 1950 by Waldenström, the initially reported treatment option has remained until today and is the core of the basic therapeutic strategy of inducing remission with ...
Stefan, Lueth, Ansgar W, Lohse
+9 more sources
Current Pediatric Reviews, 2015 Autoimmune hepatitis (AIH) is a severe hepatopathy characterised by female preponderance, hypertransaminasaemia, elevated levels of immunoglobulin (IgG), presence of serum autoantibodies and, histologically, by interface hepatitis. AIH occurs both in adults and children, being particularly aggressive in the latter.
Longhi, Maria Serena +2 more
openaire +6 more sources