Results 101 to 110 of about 29,121 (207)

Explainable Machine Learning With Hybrid Feature Selection for Thyroid Disease Classification: A Case Study in Bangladesh

open access: yesEngineering Reports, Volume 8, Issue 8, August 2026.
Our research establishes a hybrid feature selection and ensemble machine learning pipeline for the classification of euthyroid, hyperthyroid, hypothyroid, and subclinical hypo‐ and hyperthyroid disorders. Variance Threshold with Backward Feature Elimination attained nearly 100% accuracy, while SHAP and LIME clarified the significance of features and ...
Md. Minhajul Abedin   +5 more
wiley   +1 more source

Association Between Dietary Anthocyanidin Intake and Thyroid Autoimmunity: A Cross‐Sectional Study From NHANES (2007–2010)

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Despite extensive documentation of the immunomodulatory effects of anthocyanidins, population‐based epidemiological studies have yet to elucidate their association with thyroid autoimmunity (TAI). Methods Using flavonoid intake data from the Flavonoid and Anthocyanidin Database (FNDDS) and 2007–2010 National Health and Nutrition ...
Mingkuan Chen   +6 more
wiley   +1 more source

The Effect of Simvastatin on Thyroid Function in Experimental Autoimmune Thyroiditis Induced in Rats

open access: yesIraqi Journal of Pharmaceutical Sciences
Autoimmune thyroiditis or Hashimoto’s thyroiditis (HT): is the most common autoimmune thyroid disease. is characterized by marked lymphocytic infiltration and the presence of serum autoantibodies against Thyroid peroxidase (TPO) and Thyroglobulin (TG ...
Yaqeen Talib Mohammed   +2 more
doaj   +1 more source

Long‐Term Outcomes of Surgical Management for Submandibular Sialolithiasis: Gland Resection Versus Preservation

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 4, August 2026.
ABSTRACT Objective Describe long‐term outcomes of submandibular sialolithiasis treatment, comparing gland‐preserving procedures to gland resection. Methods This retrospective cohort study with prospective patient‐reported outcome assessment study included all patients who underwent initial surgical management of submandibular sialolithiasis by a single
Claire Orth   +5 more
wiley   +1 more source

Autoimmune Thyroiditis as Initial Presentation of Systemic Lupus Erythematosus Complicated by Massive Ascites: A Case Report

open access: yesJournal of the ASEAN Federation of Endocrine Societies, 2017
Autoimmune thyroiditis in the course of other autoimmune diseases such as systemic lupus erythematosus (SLE) is common because these disorders are attributed to the production of autoantibodies against various autoantigens.
Noor Rafhati Adyani Abdullah   +1 more
doaj  

The Toll‐Like Receptor Signalling Pathway Is Altered in iPSC‐Derived Cortical Networks From People With Bipolar Disorder

open access: yesBipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Background Induced pluripotent stem cell (iPSC)‐derived brain cells are widely utilised as in vitro models for several neuropsychiatric disorders, as they retain the donor's genetic profile, offering a unique opportunity to study living human brain cells and perform controlled experimental manipulations.
Bruna Panizzutti   +19 more
wiley   +1 more source

The discovery of thyroid autoimmunity

open access: yesImmunology Today, 1991
In 1951 there were not many places where a newly minted PhD could go to learn immunology. Michael Heidelberger was at Columbia working on the immunochemistry of polysaccharides and Ernest Witebsky in Buffalo was engaged mostly in studying human blood groups and isolating the blood group substances.
openaire   +2 more sources

Concurrent Hashimoto's Encephalopathy and Papillary Thyroid Carcinoma: A Case Report

open access: yesClinical and Experimental Neuroimmunology, Volume 17, Issue 3, August 2026.
ABSTRACT Background Hashimoto's encephalopathy (HE) is a rare steroid‐responsive autoimmune syndrome. Although HE is associated with anti‐thyroid antibodies, its concurrence with malignant thyroid tumors has rarely been described and its clinical implications remain poorly understood.
Ryo Hara   +12 more
wiley   +1 more source

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6584-6594, August 2026.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas   +11 more
wiley   +1 more source

Long‐Term Cancer and Mortality After Thymectomy

open access: yesEuropean Journal of Neurology, Volume 33, Issue 8, August 2026.
In a propensity score‐matched study comparing 398 thymectomy patients with 398 cardiothoracic controls over 10 years, thymectomy was not associated with excess all‐cause mortality (HR 0.78; 95% CI 0.54–1.13) or new malignancy (4.3% in both groups). Indication‐stratified analysis revealed heterogeneity: thymic malignancy carried significantly higher ...
Shahar Shelly   +7 more
wiley   +1 more source

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