Results 71 to 80 of about 231,557 (237)

Effect of Anti‐IL‐23 and Anti‐IL‐17 Therapy on Darier Disease: A Case Series

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Darier disease is a rare ATP2A2‐related genodermatosis for which therapeutic options remain limited, as acitretin is often constrained by toxicity and teratogenicity. In this retrospective real‐world case series of eight patients, anti‐IL‐17 therapy showed a more consistent early signal of clinical benefit than anti‐IL‐23 therapy, with greater
Maione Vincenzo, Zanghi Silvia, Catapano Cecilia, Bighetti Stefano, Cattaneo Isacco, Venturini Marina, Bettolini Luca   +6 more
wiley   +1 more source

Polyglandular Autoimmune Syndrome Type III with Primary Hypoparathyroidism [PDF]

Endocrinology and Metabolism, 2013
Polyglandular autoimmune syndrome is defined as multiple endocrine gland insufficiencies accompanied by autoimmune diseases of the endocrine and nonendocrine system.
Sang Jin Kim, Sang-Yoon Kim, Han-Byul Kim, Hyukwon Chang, Ho-Chan Cho   +4 more
doaj   +1 more source

Autoimmune Thyroid Disorders [PDF]

ISRN Endocrinology, 2013
Purpose of Review. Studies have been published in the field of autoimmune thyroid diseases since January 2005. The review is organized into areas of etiology, autoimmune features, autoantibodies, mechanism of thyroid cell injury, B-cell responses, and T-cell responses.
M. A. Iddah, B. N. Macharia
openaire   +2 more sources

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes, Florian Buehning, Tobias Lerchner, Julia Vogel, Raluca I. Mincu, Matthias Totzeck, Tienush Rassaf, Lars Michel   +7 more
wiley   +1 more source

Understanding the Challenges of Hashimoto's Thyroiditis: Perspectives on Diagnosis, Treatment, and Associated Conditions

Journal of Education, Health and Sport
Introduction: Hashimoto's thyroiditis is a prevalent autoimmune disease among the population. With the progress in diagnostic and research techniques, it has come to light that Hashimoto's thyroiditis is linked to a higher likelihood of developing other
Klaudia Brygida Kułak, Karolina Palacz, Katarzyna Gadżała, Izabela Janik, Marzena Pliszka, Katarzyna Chamera-Cyrek, Anna Maria Koman   +6 more
doaj   +1 more source

Basedow’s disease with associated features of Hashimoto’s thyroiditis based on histopathological findings

BMC Endocrine Disorders, 2020
Background Basedow’s disease and Hashimoto’s thyroiditis are autoimmune thyroid disorders and usually diagnosed with elevation of serum autoimmune antibodies.
Megumi Horiya, Takatoshi Anno, Fumiko Kawasaki, Yuichiro Iwamoto, Shintaro Irie, Yasumasa Monobe, Koichi Tomoda, Kohei Kaku, Shuhei Nakanishi, Hideaki Kaneto   +9 more
doaj   +1 more source

Autoimmune thyroid disorders

Autoimmunity Reviews, 2015
Autoimmune thyroid diseases (AITD) result from a dysregulation of the immune system leading to an immune attack on the thyroid. AITD are T cell-mediated organ-specific autoimmune disorders. The prevalence of AITD is estimated to be 5%; however, the prevalence of antithyroid antibodies may be even higher.
ANTONELLI, ALESSANDRO, Ferrari SM, Corrado A, Di Domenicantonio A, Fallahi P.   +4 more
openaire   +2 more sources

Emerging Paediatric Uses of Dupilumab Beyond Approvals

Clinical &Experimental Allergy, EarlyView.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese, Anna Calamita, Diletta D'Angelo, Alessia Marseglia, Esther Mesa Lombardero, Sara Pedersoli, Micol Tedeschi, Mara De Amici, Sara Manti, Valeria Brazzelli, Amelia Licari, Gian Luigi Marseglia   +11 more
wiley   +1 more source

Features of the composition and correction of gut microbiota with metaprebiotic as one of the components of complex treatment of patients with autoimmune thyroiditis

Лечащий Врач
Background. In recent years, researchers pay close attention to studying the composition of the gut microbiota and its effect on the course of autoimmune diseases.Objectives.
N. V. Sturov, A. A. Kostenko, E. M. Shimkevich   +2 more
doaj   +1 more source

What Endocrinologists Should Know About Iodine: Population Deficiency, Individual Excess and Misinformation in the United Kingdom

Clinical Endocrinology, EarlyView.
ABSTRACT Iodine deficiency, once considered eliminated in the United Kingdom, has re‐emerged, particularly among women of reproductive age, in whom requirements are increased during pregnancy and lactation. The declining consumption of dairy and white fish, the emerging use of unfortified plant‐based milk alternatives, and the absence of a national ...
Peter N. Taylor, Malcolm Prentice, Sarah Bath, Emilie Combet, Nadia Schoenmakers, Vicki E. Smith, Fraser W. Gibb, Nicola Zammitt, Onyebuchi Okosieme, Kristien Boelaert, John Lazarus, Mark Vanderpump   +11 more
wiley   +1 more source