Results 121 to 130 of about 28,173 (225)

Azathioprine in the Management of Autoimmune Uveitis

Ocular Immunology and Inflammation, 2008
To evaluate the role of azathioprine as an immunosuppressive for steroid-resistant autoimmune uveitis (AIU).Patients using oral prednisolone for active AIU without clinical response were recruited. A standard protocol of oral prednisolone and azathioprine was used.Twenty-seven patients participated in the study: 3 with anterior uveitis, 1 pars planitis,
Pacheco, Patricio A., Taylor, Simon R.J., Cuchacovich Turteltaub, Miguel, Diaz, Gonzalo V.   +3 more
openaire   +3 more sources

Local Delivery of CTLA-4 Blockade Inhibits Growth of Pancreatic Tumors [PDF]

, 2016
Immune checkpoint blockade has demonstrated great potential in activating antitumor immunity. Ipilimumab is a monoclonal antibody which targets cytotoxic T-lymphocyte antigen-4. CTLA-4 belongs to the CD28 class of receptors and is found on the surface of
Baltz, Jack
core   +2 more sources

Macrophages and Uveitis in Experimental Animal Models

Mediators of Inflammation, 2015
Resident and infiltrated macrophages play relevant roles in uveitis as effectors of innate immunity and inductors of acquired immunity. They are major effectors of tissue damage in uveitis and are also considered to be potent antigen-presenting cells. In
Salvador Mérida, Elena Palacios, Amparo Navea, Francisco Bosch-Morell   +3 more
doaj   +1 more source

Development of cytomegalovirus (CMV) immune recovery uveitis is associated with Th17 cell depletion and poor systemic CMV-specific T cell responses. [PDF]

, 2011
Backgroundthe immune reconstitution inflammatory syndromes (IRIS) are a spectrum of inflammatory conditions associated with opportunistic infections and occurring in approximately16% of human immunodeficiency type 1 (HIV-1)-infected patients given ...
Hartigan-O'Connor, Dennis J, Jacobson, Mark A, Sinclair, Elizabeth, Studies of Ocular Complications of AIDS Research Group, Tan, Qi Xuan   +4 more
core   +1 more source

Role of Cytokines in experimental and clinical uveitis

Indian Journal of Ophthalmology, 2001
Uveitis is a major cause of visual impairment. Experimental autoimmune uveitis mimics the clinical conditions of posterior uveitis in many ways. T-cells (particularly CD4[+] helper-T-cells) have been shown to play an important role in pathogenesis
Singh Vijay, Rai Geeta, Agarwal Shyam
doaj  

Oral vitamins C and E as additional treatment in patients with acute anterior uveitis [PDF]

, 1999
AIM: To investigate the effect of additional oral vitamins C and E on acute anterior uveitis. METHODS: A placebo controlled double masked study on the effect of vitamin C 500 mg in combination ...
Baarsma, G.S. (Seerp), Mulder, P.G.H. (Paul), Rooij, J. (Jeroen) van, Schwartzenberg, S.G.W.S. (Sicco) thoe   +3 more
core  

Immune checkpoints in a genetically engineered mouse model of spontaneous autoimmune uveitis. [PDF]

J Immunol
Yin M, Hiam-Galvez KJ, Proekt I, Chan J, Hu Y, Lowell CA, Caspi RR, Spitzer MH, Anderson MS, DeFranco AL.   +9 more
europepmc   +1 more source

Therapeutic Effect of Baicalin-Loaded Thermosensitive Liposomal Hydrogel in Autoimmune Uveitis. [PDF]

ACS Omega
Zhu L, Li N, Zhang R, Shao Y, Lai J.
europepmc   +1 more source

Lipoxin A4 (LXA4) as a Potential Drug for Autoimmune Uveitis [PDF]

Balkan Med J
Das UN.
europepmc   +1 more source

Gut microbial alterations associated with the exacerbation of experimental autoimmune uveitis in PGRN-deficient mice. [PDF]

Front Immunol
Zhou W, Zhang S, Wang C.
europepmc   +1 more source