Autoimmune uveitis - Open Access .click

Results 71 to 80 of about 28,173 (225)

Higher complement C4 gene copy number constitutes a shared genetic risk factor for giant cell arteritis and IgA vasculitis

Arthritis &Rheumatology, Accepted Article.
Objective Low copy number (CN) of complement C4 isoforms and high CN of retroviral HERV‐K elements are known risk factors for many immune‐mediated inflammatory diseases (IMIDs), often showing sex‐biased effects. Here, we assessed whether CN variation within the C4 gene contributes to giant cell arteritis (GCA) and IgA vasculitis (IgAV), two complex ...
Laura Martínez‐Gutiérrez +296 more
wiley +1 more source

Ropivacaine vs tetracaine in topical anesthesia for intravitreal injection [PDF]

, 2015
Aim: The object of the study was to evaluate the long term efficacy and safety of ropivacaine 0,5% vs tetracaine 0,5% for topical anesthesia in intravitreal injection of dexamethasone in patients with diabetic macular edema (DME) and anti-vascular ...
COLLINI, Saul +6 more
core +1 more source

Voclosporin‐induced gingival enlargement: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background Drug‐influenced gingival enlargement (DIGE) is a recognized adverse effect of certain medications, particularly immunosuppressants like cyclosporin and tacrolimus. However, there have been no documented cases of DIGE associated with voclosporin, a newer calcineurin inhibitor used primarily to treat lupus nephritis.
Francesca Racca, Jessica M. Greco, Dimitris N. Tatakis +2 more
wiley +1 more source

Administration of a peptide inhibitor of alpha4-integrin inhibits the development of experimental autoimmune uveitis [PDF]

, 2005
Recruitment of lymphocytes into the retina and to the vitreous during the development of experimental autoimmune uveitis (EAU) is governed by factors such as the state of activation of inflammatory cells and the repertoire of adhesion molecules expressed
Commodaro, Alessandra G. +8 more
core +1 more source

Monocytes with trained immunity–like signatures are associated with acute anterior uveitis in ankylosing spondylitis

Interdisciplinary Medicine, EarlyView.
In ankylosing spondylitis‐acute anterior uveitis (AS‐AAU), trained immunity monocytes (Mono‐TI) differentiate into macrophages in the eye, retaining trained immunity features. Mono‐TI cells secrete pro‐inflammatory cytokines and chemokines, including IL‐1β, TNF‐α, and CCL3.
Yimeng Sun +13 more
wiley +1 more source

Doyne lecture 2016:intraocular health and the many faces of inflammation [PDF]

, 2016
Dogma for reasons of immune privilege including sequestration (sic) of ocular antigen, lack of lymphatic and immune competent cells in the vital tissues of the eye has long evaporated.
Dick, A D
core +5 more sources

Asprosin as a Potential Link Between Vascular Inflammation and Disease Activity in Behçet's Disease

Journal of Clinical Laboratory Analysis, EarlyView.
Serum asprosin levels are significantly elevated in patients with Behçet's disease compared to healthy controls. Asprosin concentrations increase progressively with disease activity and are strongly associated with vascular involvement and uveitis, suggesting a potential role as a biomarker of vascular inflammation and disease severity.
Zeynep Kaya +6 more
wiley +1 more source

High prevalence of anelloviruses in vitreous fluid of children with seasonal hyperacute panuveitis. [PDF]

, 2012
Seasonal hyperacute panuveitis (SHAPU) is a potentially blinding ocular disease occurring in Nepal that principally affects young children. Random amplification of partially purified vitreous fluid (VF)-derived nucleic acid revealed the presence of human
Baarsma, G Seerp +8 more
core +1 more source

Risk of uveitis among children with autoimmune diseases: a nationwide matched-cohort study of 3,643 cases

Frontiers in Immunology
BackgroundPediatric uveitis, though accounting for less than 10% of all uveitis cases, presents significant diagnostic and therapeutic challenges due to its asymptomatic onset and potential for severe, vision-threatening complications.
De-Yi Liu +38 more
doaj +1 more source

Frequency of Brucella canis seropositivity in at‐risk dogs referred for veterinary care in the UK

Veterinary Record, EarlyView.
Abstract Background Brucella canis is a canine pathogen of zoonotic concern. It is not considered endemic in the UK, with most infections diagnosed in travelled dogs or their offspring. Methods Between March 2021 and December 2022, all dogs with a history of travel outside of the UK or clinical signs compatible with brucellosis referred for veterinary ...
Josh Kennils +3 more
wiley +1 more source

uveitis
autoimmune diseases
3. good health

humans
animals
disease models, animal

autoimmunity
female
retina