Results 211 to 220 of about 221,041 (347)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

The impact of familial autoimmunity and familial lupus on the clinical presentations and disease outcomes of SLE patients in the United Arab Emirates. [PDF]

BMC Rheumatol
Al Dhaheri A, Alblooshi H, Bharathan A, Alneyadi A, Al Ali M, Alzaabi A, Trad J, Chandrasekhar Nair S, Aljaberi N.   +8 more
europepmc   +1 more source

TGF-β inhibitor Smad7 regulates dendritic cell-induced autoimmunity [PDF]

, 2017
Dominika Lukas, Nir Yogev, Junda M. Kel, Tommy Regen, Ilgiz A. Mufazalov, Yilang Tang, Florian Wanke, Boris Reizis, Werner Müller, Florian C. Kurschus, Marco Prinz, Ingo Kleiter, Björn E. Clausen, Ari Waisman   +13 more
openalex   +1 more source

Microphysiological Systems of Lymphatics and Immune Organs

Advanced Healthcare Materials, EarlyView.
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain, Ankur Singh, Andrés J. García   +2 more
wiley   +1 more source

Exosomes in Autoimmunity: Mediators of Autoantigen Presentation and Targets for Therapeutic Intervention in Autoimmune Diseases. [PDF]

J Clin Immunol
Almohaimeed HM, Almars AI, Tounsi WA, Mohammedsaleh ZM, Panigrahi R, Singh I, Singh S, Dhara B, Uti DE.   +8 more
europepmc   +1 more source

A20 in Kidney Transplantation and Autoimmunity [PDF]

Andreas Kommer, Myriam Meineck, Paul Claßen, Julia Weinmann‐Menke   +3 more
openalex   +1 more source

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source

AUTOIMMUNITY AND AUTOIMMUNE DISEASE

British Journal of Anaesthesia, 1979
openaire   +2 more sources

Sjögren Syndrome Candidate Autoantigen AQP5 Triggers AQP4 CNS Autoimmunity Through Self-Antigen Mimicry. [PDF]

Neurol Neuroimmunol Neuroinflamm
Moseley CE, Sagan S, Boquett JA, Spencer CM, Hollenbach JA, Sobel RA, Rothbard JB, Steinman L, Sabatino JJ, Zamvil SS.   +9 more
europepmc   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source