Results 211 to 220 of about 339,261 (412)

Translocation of a gut pathobiont drives autoimmunity in mice and humans

open access: yesScience, 2018
S. Vieira   +16 more
semanticscholar   +1 more source

In Vivo Reprogramming of Tissue‐Derived Extracellular Vesicles for Treating Chronic Tissue Injury Through Metabolic Engineering

open access: yesAdvanced Science, EarlyView.
Inspired by exercise‐induced metabolic rewiring and EV secretion, this study shows that in vivo metabolic engineering strategy can reprogram EV secretion pattern and simultaneously attenuate multiple tissue injury in CKD status, highlighting that it is a potential strategy for treating diverse chronic diseases.
Meng Zhao   +11 more
wiley   +1 more source

(4) AUTOIMMUNITY AND RENAL DISEASES

open access: bronze, 1967
Seiichi Shibata, Toshihiko Nagasawa
openalex   +2 more sources

Targeted Delivery of α‐ketoglutarate to Macrophages in Bone: A Novel Therapeutic Strategy for Improving Fracture Healing in Type 2 Diabetes

open access: yesAdvanced Science, EarlyView.
The study reveals that glutaminolysis in macrophages is inhibited under type 2 diabetes mellitus (T2DM) conditions, which impedes fracture healing by reducing bone morphogenetic protein 2 (BMP2) production through increased cytosine methylation on the promoter.
Jing Wang   +12 more
wiley   +1 more source

Insights into Siglec‐7 Binding to Gangliosides: NMR Protein Assignment and the Impact of Ligand Flexibility

open access: yesAdvanced Science, EarlyView.
The molecular recognition of the sugar moiety of GD3 and Gb3 (globotriaosylceramide) derivatives by Siglec‐7 has been thoroughly studied offering insights for cancer diagnostics and therapies. A combination of structural biology techniques, nuclear magnetic resonance (NMR) spectroscopy, physicochemical analysis, and in silico methods suggested that ...
Cristina Di Carluccio   +15 more
wiley   +1 more source

Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes

open access: yesScience, 2002
M. Dudley   +18 more
semanticscholar   +1 more source

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