Results 71 to 80 of about 279,347 (206)

Audio-vestibular symptoms in systemic autoimmune diseases [PDF]

, 2018
Immune-mediated inner ear disease can be primary, when the autoimmune response is against the inner ear, or secondary. The latter is characterized by the involvement of the ear in the presence of systemic autoimmune conditions. Sensorineural hearing loss
Adelchi, Croce, D'AGUANNO, VITTORIO, DE VINCENTIIS, Marco, DE VIRGILIO, ARMANDO, DI STADIO, Arianna, GRECO, Antonio, LONGO, Lucia, RALLI, MASSIMO   +7 more
core   +1 more source

Sarcoidosis as an Autoimmune Disease

Frontiers in Immunology, 2020
Despite the large number of performed studies, the etiology and pathogenesis of sarcoidosis still remain unknown. Most researchers allude to the possible autoimmune or immune-mediated genesis of the disease.
Anna A. Starshinova, Anna M. Malkova, Natalia Y. Basantsova, Natalia Y. Basantsova, Yulia S. Zinchenko, Yulia S. Zinchenko, Igor V. Kudryavtsev, Igor V. Kudryavtsev, Igor V. Kudryavtsev, Gennadiy A. Ershov, Lidia A. Soprun, Vera A. Mayevskaya, Leonid P. Churilov, Leonid P. Churilov, Piotr K. Yablonskiy, Piotr K. Yablonskiy   +15 more
doaj   +1 more source

The roles of metabolic profiles and intracellular signaling pathways of tumor microenvironment cells in angiogenesis of solid tumors

Cell Communication and Signaling, 2022
Innate and adaptive immune cells patrol and survey throughout the human body and sometimes reside in the tumor microenvironment (TME) with a variety of cell types and nutrients that may differ from those in which they developed.
Hamidreza Zalpoor, Fatemeh Aziziyan, Mahsa Liaghat, Maryam Bakhtiyari, Abdullatif Akbari, Mohsen Nabi-Afjadi, Razieh Forghaniesfidvajani, Nima Rezaei   +7 more
doaj   +1 more source

Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity. [PDF]

, 2007
Peroxisome proliferator-activated receptor (PPAR)alpha is a nuclear receptor that mediates gender differences in lipid metabolism. PPARalpha also functions to control inflammatory responses by repressing the activity of nuclear factor kappaB (NF-kappaB ...
Baranzini, Sergio E, Crowell, Andrea, Dunn, Shannon E, Loh, John, Oksenberg, Jorge, Ousman, Shalina S, Sobel, Raymond A, Steinman, Lawrence, Youssef, Sawsan, Zuniga, Luis   +9 more
core  

Editorial: tertiary lymphoid organs (TLOs): powerhouses of disease immunity [PDF]

, 2017
No abstract ...
Habenicht, Andreas J.R., Maffia, Pasquale, Mohanta, Sarajo, Yin, Changjun   +3 more
core   +2 more sources

Potential Roles of Antiphospholipid Antibodies in Generating Platelet-C4d in Systemic Lupus Erythematosus

Antibodies, 2017
Premature, accelerated onset of atherothrombotic disease is prevalent in patients with systemic lupus erythematosus (SLE). Most, if not all, atherothrombotic diseases are likely to involve platelets and complement.
Chau-Ching Liu, Travis Schofield, Amy Tang, Susan Manzi, Joseph M. Ahearn   +4 more
doaj   +1 more source

Anti-Idiotypic Agonistic Antibodies: Candidates for the Role of Universal Remedy

Antibodies, 2020
Anti-idiotypic antibodies (anti-IDs) were discovered at the very beginning of the 20th century and have attracted attention of researchers for many years. Nowadays, there are five known types of anti-IDs: α, β, γ, ε, and δ. Due to the ability of internal-
Aliya K. Stanova, Varvara A. Ryabkova, Sergei V. Tillib, Vladimir J. Utekhin, Leonid P. Churilov, Yehuda Shoenfeld   +5 more
doaj   +1 more source

Landscape of stimulation-responsive chromatin across diverse human immune cells. [PDF]

, 2019
A hallmark of the immune system is the interplay among specialized cell types transitioning between resting and stimulated states. The gene regulatory landscape of this dynamic system has not been fully characterized in human cells.
Anderson, Mark S, Blaeschke, Franziska, Burt, Trevor D, Calderon, Diego, Criswell, Lindsey A, Gao, Ziyue, Greenleaf, William J, Kathiria, Arwa, Knowles, David A, Lescano, Ninnia, Marson, Alexander, Mezger, Anja, Müller, Fabian, Nguyen, Michelle LT, Nguyen, Vinh, Parent, Audrey V, Pritchard, Jonathan K, Ribado, Jessica V, Trombetta, John, Wu, Beijing   +19 more
core  

Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity. [PDF]

, 2018
Regulatory T cells (Tregs) are critical for maintaining immune homeostasis, but their presence in tumor tissues impairs anti-tumor immunity and portends poor prognoses in cancer patients.
Abnousian, Arbi, Bluestone, Jeffrey A, DuPage, Michel, Fong, Lawrence, Harwin, Tory, Mahuron, Kelly, Pagani, Massimiliano, Pai, Chien-Chun, Quiros, Jason, Ranzani, Valeria, Rosenblum, Michael D, Silveria, Stephanie, Van Gool, Frederic, Wang, David, Young, Arabella   +14 more
core   +2 more sources

Montelukast Disposition: No Indication of Transporter-Mediated Uptake in OATP2B1 and OATP1B1 Expressing HEK293 Cells

Pharmaceutics, 2015
Clinical studies with montelukast show variability in effect and polymorphic OATP2B1-dependent absorption has previously been implicated as a possible cause. This claim has been challenged with conflicting data and here we used OATP2B1-transfected HEK293
Marie Brännström, Pär Nordell, Britta Bonn, Andrew M. Davis, Anna-Pia Palmgren, Constanze Hilgendorf, Katarina Rubin, Ken Grime   +7 more
doaj   +1 more source