Results 121 to 130 of about 4,410 (179)
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A complication of adrenaline autoinjectors
Archives of Disease in Childhood, 2017A 3-year-old boy with nut allergy received an EpiPen dose by the recommended ‘Swing and Jab’ technique for anaphylaxis. This resulted in a severe laceration (figure 1) and subsequent 9 cm scar (figure 2). Figure 1 Image showing laceration to thigh from EpiPen use by ‘Swing and Jab’ method. Figure 2 Scar following laceration, 3 years later.
David, Tuthill +3 more
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A framework to optimize spring-driven autoinjectors
International Journal of Pharmaceutics, 2022The major challenges in the optimization of autoinjectors lie in developing an accurate model and meeting competing requirements. We have developed a computational model for spring-driven autoinjectors, which can accurately predict the kinematics of the syringe barrel, needle displacement (travel distance) at the start of drug delivery, and injection ...
Xiaoxu, Zhong +2 more
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Practices in the prescription of adrenaline autoinjectors
Pediatric Allergy and Immunology, 2011To cite this article: Johnson MJ, Foote KD, Moyses HE, Roberts G. Practices in the prescription of adrenaline autoinjectors. Pediatr Allergy Immunol 2011; Doi: 10.1111/j.1399‐3038.2011.01221.xAbstractBackground: Anecdotally, the prescription of adrenaline autoinjectors seems to be very variable. We aimed to survey the practice in this area and look at
Johnson, Mark J. +3 more
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Fremanezumab Autoinjector Pen for the Prevention of Migraine
Therapeutic Delivery, 2021Ajovy (fremanezumab, Teva Pharmaceuticals, Israel) is a fully humanized monoclonal antibody that selectively binds both isoforms of the calcitonin gene-related peptide. Calcitonin gene-related peptide is a 37-amino acid neuropeptide involved in central and peripheral pathophysiological events in migraine.
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Epinephrine Autoinjector Refill History in an HMO
Current Allergy and Asthma Reports, 2010Epinephrine can be lifesaving in episodes of anaphylaxis, yet it is underprescribed and underused. Tracking of epinephrine refills over time for patients with a diagnosis of anaphylaxis has not been reported. This study reports on the refill history of 14,677 patients in a large HMO who received an initial dispensing of EpiPen (Dey Pharma, Basking ...
Michael S, Kaplan +2 more
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Anaphylaxis: A Payor's Perspective on Epinephrine Autoinjectors
The American Journal of Medicine, 2014The scope of expenditures due to anaphylaxis likely is underestimated by health care payors because anaphylaxis is underdiagnosed and, when reported, most costs of anaphylaxis borne by payors relate to direct medical expenses. Direct costs of anaphylaxis have been estimated at $1.2 billion per year, with direct expenditures of $294 million for ...
Jeffrey D, Dunn, David A, Sclar
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The use of adrenaline autoinjectors by children and teenagers
Clinical & Experimental Allergy, 2011SummaryBackgroundAlthough adrenaline is recommended as first line treatment for anaphylaxis, it is often not utilized. There has been a debate about when adrenaline autoinjectors should be prescribed and how many should be dispensed.ObjectivesTo see how many adrenaline autoinjectors were used during anaphylactic reactions and to determine why they were
Noimark, L. +15 more
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Atropine Autoinjector Use as a Suicidal Gesture
The Journal of Emergency Medicine, 2008Atropine autoinjectors are used by the U.S. military as pre-hospital first-line therapy for nerve agent exposure. This case report examines the misuse of these devices in a suicide attempt. An anticholinergic toxidrome resulted from this misuse. The patient was successfully treated.
Charles L, Taylor, Shawn F, Taylor
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