Results 101 to 110 of about 238,159 (194)

Mitochondrial targets in ischaemic heart disease and heart failure, and their potential for a more efficient clinical translation. A scientific statement of the ESC Working Group on Cellular Biology of the Heart and the ESC Working Group on Myocardial Function

European Journal of Heart Failure, EarlyView.
Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard, Mahmoud Abdellatif, Ioanna Andreadou, Christian Bär, Luc Bertrand, Bianca J.J.M. Brundel, Gemma Chiva‐Blanch, Sean M. Davidson, Dana Dawson, Fabio Di Lisa, Paul Evans, Zoltan Giricz, Derek J. Hausenloy, Petra Kleinbongard, Frank Lezoualc'h, Elisa Liehn, Christoph Maack, Ange Maguy, Elizabeth Murphy, Cinzia Perrino, Maurizio Pesce, Peter P. Rainer, Katrin Streckfuss‐Bömeke, Matthias Thielmann, Rong Tian, Carlo G. Tocchetti, Jolanda Van Der Velden, Sophie Van Linthout, Serena Zacchigna, Thomas Krieg   +29 more
wiley   +1 more source

Pathways to Progressive Disability in Multiple Sclerosis: The Role of Glial Cells in Chronic CNS Inflammation

Glia, EarlyView.
ABSTRACT Multiple sclerosis (MS) is the most common non‐infectious inflammatory CNS disease, characterized by progressive neurodegeneration and focal demyelinated lesions. Traditionally considered an autoimmune disease, MS is driven by the immune system's attack on CNS myelin, resulting in cumulative disability.
Volker Siffrin
wiley   +1 more source

Progress of non‐motor symptoms in early‐onset Parkinson's disease

Ibrain, EarlyView.
This study reviews the research progress related to non‐motor symptoms (NMS) in patients with early onset Parkinson's disease (EOPD), including neuropsychiatric symptoms, autonomic dysfunction, sleep disorders, and sensory disorders and also summarizes the characteristics of NMS in the genetic form of Parkinson's disease (PD).
Fanshi Zhang, Aidi Luo, Shusheng Liao, Mei Liu, Jun Zhang, Zucai Xu   +5 more
wiley   +1 more source

Epigenetic reprogramming in multiple myeloma—Challenges and opportunities

International Journal of Cancer, EarlyView.
Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar, Lev M. Kats, Emily Gruber   +2 more
wiley   +1 more source

Epidermolysis bullosa for primary care providers: A practical review

Journal of General and Family Medicine, EarlyView.
Abstract Epidermolysis bullosa (EB) is a group of genetic skin diseases, which manifest as fragile skin and blistering in addition to many extracutaneous conditions. Pediatricians and primary care providers play an integral role in managing these patients with multifaceted care needs.
Kennedy Sparling, Judith O'Haver, Muayad Shahin, Amanda Damon, Nichole Halliburton, Kellie Badger, Mariam Iqneibi, Beth Moeves, Harper N. Price, Emily S. Gorell   +9 more
wiley   +1 more source

Magnetic Resonance Imaging for Dental Pulp Assessment: A Comprehensive Review

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Magnetic resonance imaging (MRI) has recently emerged as a promising modality for dental applications, offering radiation‐free imaging with superior soft tissue visualization capabilities compared to x‐ray‐based techniques such as spiral or cone beam computed tomography (CBCT).
Bing Han, Na Chen, Jin Luo, Farzaneh Afkhami, Ove A. Peters, Xiaoyan Wang   +5 more
wiley   +1 more source

A Preliminary Study on the Therapeutic Role of γδT Cells in Triple‐Negative Breast Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study was aimed to elucidate the cytotoxic effects of γδT cells on triple‐negative breast cancer (TNBC) cells and assess their antitumor efficacy in a mouse xenograft model. Furthermore, the underlying mechanisms of γδT cell action on TNBC were explored.
Shi Qiu, Qin‐Yu Han, Xian Zhao, Wen‐Jing Li, Xiang‐Qi Li   +4 more
wiley   +1 more source

Major Ozonated Autoheamotherapy Alleviates Skeletal Muscle Ischemia/Reperfusion Injury by Regulating Nrf2/HO‐1 Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Skeletal muscle ischaemia/reperfusion (I/R) injury remains a clinically significant condition characterized by muscular dystrophy. Although ozone therapy has shown protective potential against I/R injury in animal models of various organs including skeletal muscle, its precise mechanistic underpinnings require further elucidation.
Hui‐Zhuang Guo, Sheng‐Long Yu, Han‐Wei Chen   +2 more
wiley   +1 more source

Rehabilitation guidelines after autograft anterior cruciate ligament reconstruction need more graft‐specific exercise recommendations—A scoping review

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Autografts for anterior cruciate ligament reconstruction (ACLR) are primarily harvested from the quadriceps, patellar, and semitendinosus tendons. The purpose of this scoping review was to describe available recommendations for exercise‐based rehabilitation following primary ACLR with a quadriceps tendon (QT), semitendinosus tendon (ST)
Kristín Briem, Mette Kreutzfeldt Zebis, Bjarki Þór Haraldsson, Jesper Bencke, Linda Fernandes   +4 more
wiley   +1 more source

Current practice of biologic augmentation techniques to enhance the healing of meniscal repairs: A collaborative survey within the Meniscus International Network (MenIN) Study Group

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To evaluate practices and preferences among expert sports knee surgeons regarding biologic augmentation techniques in meniscal repair. Methods A 12‐question multiple‐choice survey was distributed to the Meniscus International Network (MenIN) Study Group.
James Robinson, Iain R. Murray, Gilbert Moatshe, Jorge Chahla, Luke V. Tollefson, David A. Parker, Filippo Familiari, Robert F. LaPrade, Nicholas N. DePhillipo, the Meniscus International Network (MenIN) Study Group   +9 more
wiley   +1 more source