Results 111 to 120 of about 267,252 (342)

Exploration of the mechanism of reinfusion of fresh autologous blood in type 2 diabetes mice to induce macrophage polarization and inhibit erythrocyte damage

open access: yesJournal of Diabetes Investigation
Aims/Introduction Type 2 diabetes triggers an inflammatory response that can damage red blood cells. M2 macrophages have inhibitory effects on inflammation, and play an important role in tissue damage repair and fibrosis. Autologous blood transfusion has
She‐jun Hu   +7 more
doaj   +1 more source

Expression of human adenosine deaminase in nonhuman primates after retrovirus-mediated gene transfer. [PDF]

open access: yes, 1987
Primate bone marrow cells were infected with a retroviral vector carrying the genes for human adenosine deaminase (h-ADA) and bacterial neomycin resistance (neor). The infected cells were infused back into the lethally irradiated donor animals.
Bordignon, C   +9 more
core  

Tracking intracavernously injected adipose-derived stem cells to bone marrow. [PDF]

open access: yes, 2011
The intracavernous (i.c.) injection of stem cells (SCs) has been shown to improve erectile function in various erectile dysfunction (ED) animal models. However, the tissue distribution of the injected cells remains unknown.
Banie, L   +6 more
core   +1 more source

Use of 3-D navigation to target the site of autologous blood installation for lung volume reduction in bullous emphysema [PDF]

open access: gold, 2020
Juergen Hetzel   +4 more
openalex   +1 more source

Disengaging the Engine: Histone Deacetylases 1 and 2‐Mediated Acetylation of Hexokinase‐2 Regulates Energy Metabolism in Microglia Following Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
This study demonstrates that HDAC1/2 knockout in microglia alleviates neurological deficits, preserves white matter, and accelerates hematoma clearance after ICH. HDAC1/2 inhibition reduces HK2 acetylation, shifts metabolism from glycolysis to fatty acid oxidation, reduces inflammation, and enhances phagocytosis.
Zhiwen Jiang   +9 more
wiley   +1 more source

Autologous blood transfusion during heart valve replacement surgery: a retrospective study

open access: yesZhongguo shuxue zazhi
Objective To retrospectively analyze the indexes of autologous blood transfusion during heart valve replacement, in order to provide reference for allogeneic blood transfusion during heart valve replacement surgery under direct vision.
min YE   +3 more
doaj   +1 more source

Chylothorax: A Rare Complication of Endoscopic Thoracic Sympathectomy

open access: yesİstanbul Medical Journal, 2018
Hyperhidrosis (HH) is a pathological condition of excessive secretion of the eccrine sweat glands in amounts greater than that required for physiological needs.
Mustafa Çalık   +3 more
doaj   +1 more source

A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells [PDF]

open access: yes, 2007
Viral mutational escape can reduce or abrogate recognition by the T cell receptor (TCR) of virus-specific CD8+ T cells. However, very little is known about the impact of cytotoxic T lymphocyte (CTL) epitope mutations on interactions between peptide–major
Allen, R   +18 more
core   +3 more sources

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

open access: yesAdvanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao   +16 more
wiley   +1 more source

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