Results 41 to 50 of about 2,189,298 (239)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Autotransfusão de pré-coleta imediata

Revista do Colégio Brasileiro de Cirurgiões
The practice of auto-transfusion is highly considered due to its safety and economic beneficts. It comprises two basic modalities: "Reinfusion" and "Pre-Collection" of blood.
Levão Bogossian, Aníbal da Torre Bogossian   +1 more
doaj   +1 more source

CHANGES PROTEIN SPECTRUM OF BLOOD PLASMA, WHICH DEVELOP IN PATIENTS WITH CHRONIC HEPATITIS C AFTER AUTOHAEMOTHERAPY

Медицинский вестник Юга России, 2015
Purpose: to study in patients with chronic hepatitis C the pathogenesis hematopoietic activities of autologous blood hemolysate.Materials and methods: we made an indirect MALD-TOF-mass spectrometry of blood plasma in 37 patients with chronic hepatitis C ...
D. V. Dontcov, E. F. Shin, Yu. M. Ambalov, S. V. Mordanov   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Transfusão autóloga: dois anos de aplicação no serviço de imuno-hemoterapia do Hospital de Santa Maria.

Acta Médica Portuguesa, 1991
The results of a presurgical autologous blood transfusion program for two years are analysed. 1,709 patients were submitted to this program, but appraisable results were only obtained in 1,473. In 39.54% of these ones only autologous blood was used; 19.2%
R Fleming, F Nascimento, A S Madahil
doaj   +1 more source

Prion diseases are efficiently transmitted by blood transfusion in sheep [PDF]

, 2008
The emergence of variant Creutzfeld-Jakob disease, following on from the bovine spongiform encephalopathy (BSE) epidemic, led to concerns about the potential risk of iatrogenic transmission of disease by blood transfusion and the introduction of costly ...
Foster, J., Hunter, N., Goldmann, W., Chong, A., Gonzalez, L., Siso, S., Houston, F., McCutcheon, S., Jeffrey, M.   +8 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Long-term effects of autologous bone marrow stem cell treatment in acute myocardial infarction: factors that may influence outcomes [PDF]

, 2012
AIMS: To investigate whether there are important sources of heterogeneity between the findings of different clinical trials which administer autologous stem cell treatment for acute myocardial infarction (AMI) and to evaluate what factors may influence ...
Anthony Mathur, Fisher Sheila A., Doree Carolyn, Doree, C, Mike J Clarke, Carolyn Doree (162145), Enca Martin-Rendon, Mathur Anthony, Clarke, MJ, Martin-Rendon Enca, Susan J Brunskill, Brunskill, Susan J., Susan J. Brunskill (162133), Watt, SM, Sheila A. Fisher (162124), Clifford, DM, Mike J. Clarke (162164), Watt Suzanne M., Carolyn Doree, Clifford, David M., Fisher, Sheila A., Brunskill, SJ, Suzanne M Watt, David M. Clifford (162115), Martin-Rendon, E, David M Clifford, Watt, Suzanne M., Brunskill Susan J., Clifford David M., Enca Martin-Rendon (162178), Suzanne M. Watt (162171), Fisher, SA, Doree, Caroyln, Mathur, Anthony, Clarke Mike J., Clarke, Michael, Anthony Mathur (162155), Sheila A Fisher, Martin-Rendon, Enca, Mathur, A   +39 more
core   +2 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

The Incidence and Clinical Relevance of Graft Hypertrophy After Matrix-Based Autologous Chondrocyte Implantation [PDF]

, 2011
Background: Graft hypertrophy is the most common complication of periosteal autologous chondrocyte implantation (p-ACI). Purpose: The aim of this prospective study was to analyze the development, the incidence rate, and the persistence of graft ...
Matthias F. Pietschmann, Isa Feist-Pagenstert, Peter E. Müller, Volkmar Jansson, Horng, Annie, Müller, Peter E., Thomas R. Niethammer, Feist-Pagenstert, Isa, Jansson, Volkmar, Mehmet F. Gülecyüz, Pietschmann, Matthias F., Niethammer, Thomas R., Gülecyüz, Mehmet F., Annie Horng   +13 more
core   +1 more source