Results 31 to 40 of about 23,422 (206)

EVALUATION OF QUALITATIVE AND QUANTITATIVE INDICATORS OF SUBSTITUTIONARY TRANSFUSION THERAPY IN DIFFERENT TYPES OF HEMATOPOIETIC STEM CELL TRANSPLANTATION

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2017
Relevance. Hematopoietic stem cell transplantation (HSCT) is one of methods to care patients with malignancy, hematologic and hereditary diseases; in most cases, it requires prolonged and massive substitutionary transfusion therapy.
M. A. Kucher, D. E. Pevtcov, M. A. Estrina, O. A. Makarenko, B. A. Barishev, B. V. Afanasyev   +5 more
doaj   +1 more source

Autologous Blood Transfusion in Total Hip Arthroplasty

Journal of Orthopaedic Surgery, 2004
Purpose. To determine the possibility of avoiding homologous blood transfusion during total hip arthroplasty, and to clarify the problems associated with autologous blood transfusion. Methods. A total of 253 patients received autologous blood transfusion
K Yamamoto, A Imakiire, T Masaoka, K Shinmura   +3 more
doaj   +1 more source

Autologous Transfusion after Total Knee Arthroplasty

Pakistan Armed Forces Medical Journal, 2023
Objective: To determine whether the blood lost in total knee arthroplasty surgery can be salvaged and reused using the autotransfusion technique without adverse effects and need more blood requirement. Study Design: Prospective longitudinal study.
Fayyaz Ahmed Orfi, Shafqat Hussain, Ramna Dilbar, Ali Arslan Munir, Sumbal Rana   +4 more
doaj   +1 more source

Start, Stop, Rewind, Repeat—Cyclic Exposure of Adipose Stromal Cells‐derived Cartilage Organoids to Chondrogenic and Proliferative Cues to Achieve Scaled‐up and Customizable Bone Formation by Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
This study exploits the plasticity of ASCs‐derived cartilage organoids which generate a perichondrial layer of MSCs when exposed to cyclic chondrogenic/proliferative cues. Using these organoids as building blocks, we develop (i) Phalange Shaped Tissue Engineered Cartilage (Pa‐TECs), recapitulating endochondral ossification suitable for the treatment of
Pablo Pfister, Emilien Lhospice, Andrés García‐García, Robert Paillaud, Sebastian Jung, Romain Schaller, Elisabeth A. Kappos, Claude Jaquiéry, Tarek Ismail, Dirk J. Schaefer, Michael de Wild, Ivan Martin, Alexandre Kaempfen, Arnaud Scherberich, Adrien Moya   +14 more
wiley   +1 more source

Blood transfusion practices in cardiac anaesthesia

Indian Journal of Anaesthesia, 2014
The primary reasons for blood transfusion in cardiac surgery are to correct anaemia and to improve tissue oxygen delivery. However, there is a considerable debate regarding the actual transfusion trigger at which the benefits of transfusion overweight ...
Hanumantha Rao Mangu, Aloka Samantaray, Muralidhar Anakapalli   +2 more
doaj   +1 more source

Incompatible Blood Transfusion as a Result of a Well-Known Human Error; a Case Report

طب اورژانس ایران, 2023
Blood product transfusion is a double-edged sword; it can be lifesaving in many circumstances, yet life-threatening serious complications may occur.
Mohammadreza Shahmohammadi, Firoozeh Madadi, Faranak Behnaz   +2 more
doaj   +1 more source

A Diagnostic Challenge: Post-Transfusion Purpura Unmasked After Multiple Transfusions. [PDF]

Clin Case Rep
ABSTRACT Post‐transfusion purpura (PTP) is a rare immune‐mediated post‐transfusion reaction resulting in severe thrombocytopenia. This case presents a 52‐year‐old female with profound thrombocytopenia following multiple transfusions. PTP was not initially suspected due to her history of comorbid anti‐phospholipid antibody syndrome (APS), chemotherapy ...
Thomas J, Gopalan P, Wildes TM.
europepmc   +2 more sources

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

TREM2 Drives Neutrophil Extracellular Traps‐Induced Dendritic Cell Maturation and Contributes to Lupus Progression

Advanced Science, EarlyView.
TREM2 recognizes NETs‐derived MPO to promote DC maturation and antigen presentation, thereby exacerbating the autoimmune response in SLE. Mechanistically, TREM2 activation triggers the DAP12/SYK/ERK cascade and enhances NETs internalization by DCs, which in turn activates the cGAS/STING signaling pathway.
Jingxian Shu, Jiabi Liang, Linda Zeng, Shuping Zhong, Xueling Fang, Yating Xu, Yongjian Wu, Xi Huang   +7 more
wiley   +1 more source

Safety and Efficacy of Adoptive Transfer of Stem Cell Memory Enriched Virus Specific T Cells against CMV and EBV

Advanced Science, EarlyView.
This study finds that CD8⁺ TSCM cells exhibit superior self‐renewal, differentiation, and antiviral activity. Transcriptome and epigenome analyses highlight MAPK cascade regulation in TSCM cells. In vivo, virus‐specific TSCM cells show enhanced persistence and tumor protection.
Xun‐Hong Cao, Xu‐Ying Pei, Yuan‐Yuan Zhang, Juan Xie, Jing‐Wei Tu, Zhuo‐Jun Liu, Yi‐Yang Ding, Chen‐Hua Yan, Yu‐Hong Chen, Yu Wang, Lan‐Ping Xu, Xiao‐Hui Zhang, Xiao‐Jun Huang, Xiang‐Yu Zhao   +13 more
wiley   +1 more source