Results 41 to 50 of about 23,422 (206)

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

Risk factors for allogeneic red blood cell transfusion in adult spinal deformity surgery [PDF]

Asian Spine Journal
Study Design Retrospective study. Purpose To investigate the risk factors for allogeneic red blood cell (RBC) transfusion in adult spinal deformity (ASD) surgery.
Yasushi Iijima, Toshiaki Kotani, Tsuyoshi Sakuma, Tsutomu Akazawa, Shunji Kishida, Keisuke Ueno, Shohei Ise, Yosuke Ogata, Masaya Mizutani, Yasuhiro Shiga, Shohei Minami, Seiji Ohtori   +11 more
doaj   +1 more source

Hemolysis Detected Following the Preparation and Collection of Blood in a Porcine Model Using a Syringe‐Based Aspiration Thrombectomy System for Autotransfusion

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Autologous transfusion of filtered, unwashed blood is a technique to mitigate the effects of blood loss during mechanical thrombectomy, but the degree of hemolysis resulting from this approach and guidance for blood return in this setting is not well understood.
Suhail Dohad, Mohammed M. Hoque, Jonathan H. Waters, Marc Salhanick   +3 more
wiley   +1 more source

Intraoperative blood collection without fluid replacement for cardiac surgery – A retrospective analysis

Annals of Cardiac Anaesthesia, 2022
Background: Transfusion rates in cardiac surgery are high. Aim: To determine if intraoperative autologous blood removal without volume replacement is associated with fewer homologous blood transfusions without increasing acute kidney injury.
Jennifer L Vance, Lisa Irwin, Elizabeth S Jewell, Milo Engoren   +3 more
doaj   +1 more source

Hemophilia A: An Ideal Disease for Prenatal Therapy

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada, Anthony Atala, Graça Almeida‐Porada   +2 more
wiley   +1 more source

Preliminary exploration on operation process for autologous ozonized blood transfusion

Zhongguo shuxue zazhi, 2023
Autologous ozonized blood transfusion(AOBT) is a therapy of re-transfusion of 100-200 mL of autologous blood after shaking and agitation with appropriate amount of oxygen-ozone in vitro.
Jianjun WU, Yan BAI, Yanli BAI, Zhanshan ZHA, Jing CHEN, Yahan FAN, Jiwu GONG, Shouyong HUN, Hongbing LI, Zhongjun LI, Jiajin LIN, Chunxia LIU, Fenghua LIU, Jiubo LIU, Jingling LUO, Xianjun MA, Deying MENG, Shijie MU, Mei QIN, Hui WANG, Haiyan WANG, Qiushi WANG, Quanli WANG, Xiaoning WANG, Yongjun WANG, Changsong WU, Lin WU, Jue XIE, Pu XU, Liying XU, Mingchia YANG, Yongtao YANG, Yang YU, Zebo YU, Juan ZHANG, Xiaoyu ZHOU, Xuelian ZHOU, Shuming ZHAO   +37 more
doaj   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

Bionic nanobombs target nasopharyngeal carcinoma to enhance the efficacy of chemoradiotherapy by destroying DNA damage repair systems

VIEW, EarlyView.
A bionic nanomedicine system with core–shell structure (Nm‐pAu/CP/KU) was constructed. PEGylated gold nanoparticles (pAu) were loaded with cisplatin (CP) and a radiochemotherapy sensitizer (KU‐60019) to form the core pAu/CP/KU, and homologous nasopharyngeal carcinoma cell membrane vesicles (Nm) were used as the shell.
Junhua Zhang, Xinying Xiang, Xinmin Nie, Jian Li, Rong Gui   +4 more
wiley   +1 more source

Autologous Blood Reinfusion in Patients Undergoing Bilateral Total Hip Arthroplasty

Journal of Orthopaedic Surgery, 2011
Purpose. To compare the rate and unit of allogeneic blood transfusion in one-stage bilateral total hip arthroplasty (THA) in patients with and without autologous blood reinfusion. Methods. Records of a consecutive series of 43 men and 33 women aged 25 to
Albert O Gee, Jonathan P Garino, Gwo-Chin Lee   +2 more
doaj   +1 more source

Efficiency comparison between new single‐needle dialysis and conventional double‐needle dialysis and exploration of the optimal prescription parameters for single‐needle hemodialysis

Therapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 419-427, June 2025.
Abstract Objective To compare the dialysis efficiency parameters between new single‐needle dialysis and conventional double‐needle dialysis and to explore the optimal prescription parameters for single‐needle hemodialysis. Methods This study involved a prospective, cross‐over design. Eight patients were randomly divided into two cohorts, which received
Bin Zhao, Shen Zhan, Gang Fu, Shanshan Guo, Lifang Liu, Wei Liu, Guanghui Xiao, Yuzhu Wang, Lihong Zhang   +8 more
wiley   +1 more source