Results 31 to 40 of about 1,361,764 (281)

Use of autologous mesenchymal stem cells in the combined treatment of symptomatic epilepsy

Эпилепсия и пароксизмальные состояния, 2019
This article presents the results of the clinical application of the method of transplantation of autologous bone marrow stem cells in the treatment of a patient with pharmacoresistant epilepsy, the effectiveness of combination therapy, including ...
F. P. Khlebokazov, T. V. Dokukina, N. Yu. Paramonova, S. I. Gotto, I. I. Khvostova, N. N. Misyuk, A. I. Martynenko, Е. L. Slobina, I. V. Shamruk   +8 more
doaj   +1 more source

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens, Evangelia Kiakou, Lieke de Zwart, Maurizio Miano, Eduard J. van Beers, Marc Bierings, Marije Bartels   +6 more
wiley   +1 more source

Association of Elevated Platelets and C‐Reactive Protein With Severe Disease and Poor Survival in Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.
Brian S. Lee, Shufeng Li, Srijana Davuluri, Jennifer Lee, Lorinda Chung   +4 more
wiley   +1 more source

Axoval neuropathy as initial manifestation of primary amyloidosis: report of a case submitted to bone marrow transplantation [PDF]

Arquivos de Neuro-Psiquiatria, 2004
Amyloidosis is a syndrome characterized by deposition of a highly insoluble protein material in the extracellular space that may affect several organs. It may be generalized and idiopathic (primary amyloidosis).
Orlando G. Povoas Barsottini, Adriano Arantes, Daniel Sigulem, José Mauro Kutner, Andreza Alice Feitosa Ribeiro, Luiz A. Moura, Nelson Hamerschlak   +6 more
doaj   +1 more source

Cell transplantation techniques for cartilage restoration

Journal of Cartilage & Joint Preservation, 2023
Background: Focal articular chondral lesions are a common finding among patients presenting with knee pain. If symptomatic and unresponsive to conservative treatment, cell transplantation techniques offer a unique solution to address larger defects by ...
Tristan J. Elias, Vince Morgan, Jimmy Chan, Andreas H. Gomoll, Adam B. Yanke   +4 more
doaj   +1 more source

Bioengineered Interfaces for Peripheral Nerve Sensory Restoration

Advanced Materials, EarlyView.
Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick, Salim El Hadwe, Kesi Liang, George G. Malliaras, Damiano G. Barone   +4 more
wiley   +1 more source

Receiving of neuroblasts from bone marrow stromal cells and its clinical application in patients with some diseases of nervous system

Ukrainian Neurosurgical Journal, 2006
The possibility of differentiation in vitro of mouse bone marrow stromal cells into progenitor of neuronal cells has been shown with condition of specific medias and some inductors using for cultivation.Reparation on tissue level was more ...
V. A. Yavorskaya, N. P. Voloshina, V. V. Khvysyuk, A. V. Grebenyuk, A. Yu. Gavryushin, K. V. Gretskych, O. L. Pelekhova, Yu. E. Mikulinsky, V. V. Vasilovskiy, L. F. Shestopalova, E. A. Shchegelskaya   +10 more
doaj   +1 more source

Allogeneic bone marrow transplantation in children failing prior autologous bone marrow transplantation

, 2001
Twenty-three children with de novo acute myelogenous leukemia (AML) (n = 20), secondary AML (n = 1), or non-Hodgkin's lymphoma (NHL) (n = 2) underwent allogeneic bone marrow transplantation (alloBMT) for graft failure (n = 1) or recurrent malignancy (n =
Cunningham, J. M., Rochester, R. J., Woodard, J. P., Leung, W., Hale, G. A., Tong, Xin, Bowman, L. C., Benaim, E., Heslop, H. E., Srivastava, D. K., Horwitz, E. M., Shearer, P. D.   +11 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

CD177 Deficiency Defines a Stable Subtype of Human Neutrophil Granulocytes with Tumor Promoting Activity

Advanced Science, EarlyView.
Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung, Alexander Beer, Susmita Ghosh, Ekaterina Pylaeva, Belal Alshaar, Tobias Tertel, Nils Bastian Leimkühler, Thomas Schroeder, Janine Gronewold, Nina Hagemann, Ayan Mohamud Yusuf, Benedikt Frank, Yiqiao Zhang, Dennis Nagel, Kim Schloeßer, Laura Karsch, Emily Hedtfeld, Sabrina Lohmann, Kathrin Blank, Andreas Kraus, Max Krumbein, Nastassia Kabankova, Hongxiao Wang, Almke Bader, Mathis Richter, Fengjun Zhang, Raphael Chevre, Bernd Giebel, Stephan Lang, Anika Grüneboom, Daniela Maier‐Begandt, Anja Hasenberg, Oliver Soehnlein, Hans Christian Reinhardt, Sven Heiles, Jianxu Chen, Jadwiga Jablonska, Albert Sickmann, Dirk M. Hermann, Matthias Gunzer   +39 more
wiley   +1 more source