Results 61 to 70 of about 6,119,378 (259)

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Autologous transplant: microbial contamination of hematopoietic stem cell products

The Brazilian Journal of Infectious Diseases, 2012
Hematopoietic progenitor cells from peripheral blood (HPCPB) are commonly used for autologous and allogenic transplants in patients with most various onco-hematological diseases, and despite the utilization of sterile techniques during collection and processing of these products, bacterial contamination can occur.
Almeida, Igor Dullius, Schmalfuss, Tissiana, Röhsig, Liane Marise, Goldani, Luciano Zubaran   +3 more
openaire   +6 more sources

Autologous hematopoietic stem cell transplantation in classical Hodgkin's lymphoma [PDF]

Revista Brasileira de Hematologia e Hemoterapia, 2010
Hodgkin's lymphoma has high rates of cure, but in 15% to 20% of general patients and between 35% and 40% of those in advanced stages, the disease will progress or will relapse after initial treatment. For this group, hematopoietic stem cell transplantation is considered one option of salvage therapy.To evaluate a group of 106 patients with Hodgkin's ...
Cortez, Afonso José Pereira, Dulley, Frederico Luiz, Saboya, Rosaura, Mendrone Júnior, Alfredo, Amigo Filho, Ulisses, Coracin, Fabio Luiz, Buccheri, Valéria, Linardi, Camila da Cruz Gouveia, Ruiz, Milton Artur, Chamone, Dalton de Alencar Fischer   +9 more
openaire   +5 more sources

Case study: Acute plasmoblastic leukemia presentation following effective haploidentical hematopoietic stem cell transplantation therapy

Journal of International Medical Research
Plasma cell leukemia is a rare and aggressive malignancy characterized by monoclonal gammopathy and the presence of circulating plasma cells in the peripheral blood.
Azat Karabekov, Madina Abdirgalieva, Aigerim Najipova, Vadim Kemaykin, Olga Kolesnikova, Ruzal Vildanova, Almira Manatova, Zhuldyz Kuanysh   +7 more
doaj   +1 more source

Hematopoietic stem cell transplantation in Iran: 1991 to 2008

Hematology/Oncology and Stem Cell Therapy, 2008
Since 1991,2042 first hematopoietic stem cell transplants (HSCT) have been performed at the Hematology- Oncology and stem cell Transplantation Research center at Tehran university of Medical sciences.
Ardeshir Ghavamzadeh, Kamran Alimogaddam, Mohammad Jahani, Seyedasadollah Mousavi, Masoud Iravani, Babak Bahar, Ali Khodabandeh, Farnaz Khatami, Arash Jalali   +8 more
doaj   +1 more source

Cell and Gene Therapies Manufacturing Challenges and Integrated Good Manufacturing Practices Solutions: A Lifecycle Perspective

Biotechnology and Bioengineering, EarlyView.
Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga, Udisha Singh, Sachin Dattram Pawar   +2 more
wiley   +1 more source

A nutritional index model for predicting resistance and prognosis in multiple myeloma following autologous stem cell transplantation

Discover Oncology
Background Multiple myeloma is one of the most common haematological malignancies worldwide and poses a serious threat to the life and health of the population. In recent years, more and more researchers have incorporated the prognostic nutritional index
Chulei Zhang, Dan Miao, Yunzhu Zhang, Yi Xu   +3 more
doaj   +1 more source

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

Geriatric Regenerative Medicine: Mechanisms, Strategies, and Clinical Translation

iNew Medicine, EarlyView.
The pathological drivers of aging—stem cell exhaustion, cellular senescence with SASP, and aged extracellular matrix—are precisely targeted by three corresponding mechanism‐based strategies: stem cell therapies (rejuvenation, regeneration, and replacement), senolytic/senomorphic agents (D + Q, fisetin, vaccines, and CAR‐T), and senescence‐targeting ...
Qiang Li, Chaoyang Wang, Junci Chong, Zishu Liu, Boying Wang, Shiyu Liu, Xingcai Zhang, Hengrui Liu, Shuanglin Qin, ChuTse Wu, Beidong Chen, Zhigang Chang   +11 more
wiley   +1 more source

Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection [PDF]

, 2009
Background: There is currently no effective AIDS vaccine, emphasizing the importance of developing alternative therapies. Recently, a patient was successfully transplanted with allogeneic, naturally resistant CCR5-negative (CCR5 delta 32) cells, setting ...
Trobridge, Grant D., Chiu Sum Ying, Brian C Beard, Robert A Wu, John J Rossi, Muñoz Nina M., Nina M Muñoz, John J. Rossi, Brian C. Beard, Dorothee von Laer, Laer, Dorothee von, Grant D Trobridge, Beard Brian C., Chiu, Sum Ying, Nina M. Muñoz, Kiem, Hans-Peter, Sum Ying Chiu, Trobridge Grant D., Wu, Robert A., Hans-Peter Kiem, Kiem Hans-Peter, Beard, Brian C., Wu Robert A., von Laer Dorothee, Rossi, John J., Rossi John J., Grant D. Trobridge, Robert A. Wu, Muñoz, Nina M.   +28 more
core   +2 more sources