Results 21 to 30 of about 101,866 (227)

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

Advances and applications of automata on words and trees : executive summary [PDF]

, 2011
Seminar: 10501 - Advances and Applications of Automata on Words and Trees. The aim of the seminar was to discuss and systematize the recent fast progress in automata theory and to identify important directions for future research.
Glaßer, Christian, Pin, Jean-Éric, Schweikardt, Nicole, Selivanov, Victor, Thomas, Wolfgang   +4 more
core  

Generalized Results on Monoids as Memory

, 2017
We show that some results from the theory of group automata and monoid automata still hold for more general classes of monoids and models. Extending previous work for finite automata over commutative groups, we demonstrate a context-free language that ...
D'Alessandro, Flavio, Salehi, Özlem, Say, A. C. Cem   +2 more
core   +1 more source

On the state complexity of semi-quantum finite automata [PDF]

, 2014
Some of the most interesting and important results concerning quantum finite automata are those showing that they can recognize certain languages with (much) less resources than corresponding classical finite automata \cite{Amb98,Amb09,AmYa11,Ber05,Fre09,
Gruska, Jozef, Qiu, Daowen, Zheng, Shenggen   +2 more
core   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Homology theories and tolerance automata

Discrete Mathematics, 1981
AbstractWe present three possible approaches to a homology theory of automata. Two of these require the state to possess a tolerance. This permits us to proceed by analogy with either the simplicial or the cubical theories of the topological category. The third approach describes a homology theory of automata as such.Fixed simplex theorems are stated ...
A. Muir, M. W. Warner
openaire   +2 more sources

Finite automata models of quantized systems: conceptual status and outlook [PDF]

, 2002
Since Edward Moore, finite automata theory has been inspired by physics, in particular by quantum complementarity. We review automaton complementarity, reversible automata and the connections to generalized urn models.
Svozil, Karl
core   +4 more sources

An automata characterisation for multiple context-free languages

, 2016
We introduce tree stack automata as a new class of automata with storage and identify a restricted form of tree stack automata that recognises exactly the multiple context-free languages.Comment: This is an extended version of a paper with the same title
AV Aho, D Scott, H Seki, I Guessarian, L Herrmann, MP Schützenberger, N Chomsky   +6 more
core   +1 more source